Cookies help us run our site more efficiently.

By clicking “Accept”, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. View our Privacy Policy for more information or to customize your cookie preferences.

Buildup of Metals in Body Can Worsen Heart Disease

News Feed
Wednesday, September 18, 2024

By Ernie Mundell HealthDay ReporterWEDNESDAY, Sept. 18, 2024 (HealthDay News) -- Cadmium, uranium, cobalt: These and other metals found in the environment can collect in the body and exacerbate heart disease, new research suggests."Our findings highlight the importance of considering metal exposure as a significant risk factor for atherosclerosis and cardiovascular disease," said study lead author Katlyn McGraw, a postdoctoral research scientist at Columbia University in New York City."This could lead to new prevention and treatment strategies that target metal exposure," she added in a Columbia news release.McGraw's team found that as levels of various metals rose in people's urine samples, so did evidence of stiffer, calcified arteries -- a key component of heart disease.The research was published Sept. 18 in the Journal of the American College of Cardiology.The Columbia team looked specifically at a process called atherosclerosis, the gradual hardening of blood vessels caused by a buildup of fatty plaques. Atherosclerosis can also lead to the buildup of unhealthy calcium deposits in arteries.Are exposures to environmental toxic metals a contributor to all of this?To find out, McGraw's team combed through a major database of more than 6,400 American middle-aged and older adults who were all free of heart disease when they joined the study between 2000 and 2002.Urine samples tracked each participants' levels of six environmental metal already known to have links with heart disease: Cadmium, cobalt, copper, tungsten, uranium and zinc.People are typically exposed to cadmium through tobacco smoke, while the other five metals are linked to agricultural fertilizers, batteries, oil production, welding, mining and nuclear energy production.The researchers divided participants into four groups, ranging from lowest to highest urine concentrations of the various metals.For cadmium, people placing in the highest one-quarter had levels of artery calcification that was 75% higher over the 10-year study period compared to those in the lowest quartile.For urinary tungsten, uranium and cobalt, those numbers were 45%, 39%, and 47% higher, respectively.People with the highest urinary levels of copper and zinc had calcification levels that were 33% and 57% higher, respectively, than those with the lowest levels.There were also geographic hotspots for especially high levels of metals in urine. For example, people living in Los Angeles had markedly higher urinary tungsten and uranium levels, and somewhat higher cadmium, cobalt, and copper levels, the research showed.McGraw believes the findings should serve as a wake-up call to policymakers concerned about the environment.“Pollution is the greatest environmental risk to cardiovascular health,” she said. “Given the widespread occurrence of these metals due to industrial and agricultural activities, this study calls for heightened awareness and regulatory measures to limit exposure and protect cardiovascular health.”SOURCE: Columbia University, news release, Sept. 18, 2024Copyright © 2024 HealthDay. All rights reserved.

By Ernie Mundell HealthDay ReporterWEDNESDAY, Sept. 18, 2024 (HealthDay News) -- Cadmium, uranium, cobalt: These and other metals found in the...

By Ernie Mundell HealthDay Reporter

WEDNESDAY, Sept. 18, 2024 (HealthDay News) -- Cadmium, uranium, cobalt: These and other metals found in the environment can collect in the body and exacerbate heart disease, new research suggests.

"Our findings highlight the importance of considering metal exposure as a significant risk factor for atherosclerosis and cardiovascular disease," said study lead author Katlyn McGraw, a postdoctoral research scientist at Columbia University in New York City.

"This could lead to new prevention and treatment strategies that target metal exposure," she added in a Columbia news release.

McGraw's team found that as levels of various metals rose in people's urine samples, so did evidence of stiffer, calcified arteries -- a key component of heart disease.

The research was published Sept. 18 in the Journal of the American College of Cardiology.

The Columbia team looked specifically at a process called atherosclerosis, the gradual hardening of blood vessels caused by a buildup of fatty plaques. Atherosclerosis can also lead to the buildup of unhealthy calcium deposits in arteries.

Are exposures to environmental toxic metals a contributor to all of this?

To find out, McGraw's team combed through a major database of more than 6,400 American middle-aged and older adults who were all free of heart disease when they joined the study between 2000 and 2002.

Urine samples tracked each participants' levels of six environmental metal already known to have links with heart disease: Cadmium, cobalt, copper, tungsten, uranium and zinc.

People are typically exposed to cadmium through tobacco smoke, while the other five metals are linked to agricultural fertilizers, batteries, oil production, welding, mining and nuclear energy production.

The researchers divided participants into four groups, ranging from lowest to highest urine concentrations of the various metals.

For cadmium, people placing in the highest one-quarter had levels of artery calcification that was 75% higher over the 10-year study period compared to those in the lowest quartile.

For urinary tungsten, uranium and cobalt, those numbers were 45%, 39%, and 47% higher, respectively.

People with the highest urinary levels of copper and zinc had calcification levels that were 33% and 57% higher, respectively, than those with the lowest levels.

There were also geographic hotspots for especially high levels of metals in urine. For example, people living in Los Angeles had markedly higher urinary tungsten and uranium levels, and somewhat higher cadmium, cobalt, and copper levels, the research showed.

McGraw believes the findings should serve as a wake-up call to policymakers concerned about the environment.

“Pollution is the greatest environmental risk to cardiovascular health,” she said. “Given the widespread occurrence of these metals due to industrial and agricultural activities, this study calls for heightened awareness and regulatory measures to limit exposure and protect cardiovascular health.”

SOURCE: Columbia University, news release, Sept. 18, 2024

Copyright © 2024 HealthDay. All rights reserved.

Read the full story here.
Photos courtesy of

AirPods Pro 3 review: better battery, better noise cancelling, better earbuds

Top Apple buds get upgraded sound, improved fit, live translation and built-in heart rate sensors, but are still unrepairableApple’s extremely popular AirPods Pro Bluetooth earbuds are back for their third generation with a better fit, longer battery life, built-in heart rate sensors and more effective noise cancelling, and look set to be just as ubiquitous as their predecessors.It has been three years since the last model, but the earbuds still come only in white and you really have to squint at the details to spot the difference from the previous two generations. Continue reading...

Apple’s extremely popular AirPods Pro Bluetooth earbuds are back for their third generation with a better fit, longer battery life, built-in heart rate sensors and more effective noise cancelling, and look set to be just as ubiquitous as their predecessors.The Guardian’s journalism is independent. We will earn a commission if you buy something through an affiliate link. Learn more.It has been three years since the last model, but the earbuds still come only in white and you really have to squint at the details to spot the difference from the previous two generations.The AirPods Pro 3 cost £219 (€249/$249/A$429), making them £30 cheaper in the UK than when their predecessors launched, and sit above the AirPods 4, which cost £169 with noise cancelling for those who don’t like silicone earbud tips.The shape of the earbuds has been tweaked, changing slightly the way you put them in and making them more comfortable than their predecessors for extended listening sessions of three hours or more. Five sizes of tips are included in the box, but if you didn’t get on with silicone earbuds before these won’t make a difference.The stalks are the same length as before, but the shape of the earbud has been changed to better align the tip with your ear canal. Photograph: Samuel Gibbs/The GuardianMost of the features are fairly standard for modern earbuds. Squeeze the stalks for playback controls, swipe for volume or take them out to pause the music. They support the same new features rolled out to Apple’s older earbuds, including the ability to use them as a shutter remote for the camera app and for live translation with the Translate app on the iPhone. The latter is limited to English, French, German, Portuguese and Spanish for now and isn’t available in the EU, but it works surprisingly well for casual conversations.The biggest problem is that the other person will have to rely on reading or hearing your translated speech from your iPhone. I can see it being most useful with announcements or audio guides – the kind you get on transport or in museums where you need only to translate language one way.The most interesting added hardware feature is heart rate monitoring via sensors on the side of the earbuds, similar to Apple’s Powerbeats Pro 2 fitness buds. They can be used with more than 50 workouts started in the Fitness app or a handful of third-party apps on the iPhone and proved to be roughly in line with readings from a Garmin Forerunner 970 or an Apple Watch during walks and runs. The earbuds are water-resistant to IP57 standards, which makes them much more robust against rain and sweat than before.The battery life has been increased by a third to at least eight hours of playback with noise cancelling for each charge, which is very competitive with some of the best rivals and long enough for most listening sessions.The compact flip-top case provides two full charges for a total playback time of 24 hours – six hours short of the previous generation, but five minutes in the case is enough for an hour of listening time. Photograph: Samuel Gibbs/The GuardianSpecifications Connectivity: Bluetooth 5.3, SBC, AAC, H2 chip, UWB Battery life: eight hours ANC playback (24 hours with case) Water resistance: IP57 (buds and case) Earbud dimensions: 30.9 x 19.2 x 27.0mm Earbud weight: 5.6g each Charging case dimensions: 47.2 x 62.2 x 21.8mm Charging case weight: 44g Case charging: USB-C, Qi wireless/MagSafe, Apple Watch Bigger sound and impressive noise cancellingThe silicone earbuds are infused with foam in the tips that expands slightly for a better seal for music and noise cancelling. Photograph: Samuel Gibbs/The GuardianThe sound of the third-generation AirPods Pro takes a great listen and makes it bigger. They have a wider soundscape that makes big tracks sound more expansive, while still maintaining strong but nicely controlled bass. They are detailed, well-balanced and do justice to different genres of music, with plenty of power and punch where needed. As with Apple’s other headphones, they sometimes sound a little too clinical, lacking a bit of warmth or rawness in some tracks, and they can’t quite hit the very deepest of notes for skull-rattling bass. However, few earbuds sound better at this price and size.Apple’s implementation of spatial audio for surround sound for movies remains best in class, adding to the immersion with compatible devices and services, even if spatial audio music remains a mixed bag.The AirPods Pro are the best combination of earbuds and compact case that you can easily fit in a pocket. Photograph: Samuel Gibbs/The GuardianThe improved noise cancelling is the best upgrade. Apple says it is twice as effective as the already good AirPods Pro 2, which sounds about right. In side-by-side comparisons, the AirPods Pro 3 handle street noise, including cars, horns and engines, almost as well as the class-leading Sony WH-1000XM6, which is thoroughly impressive given they are large over-ear headphones, not little earbuds.They also do a great job of dampening the troublesome higher tones such as keyboard clicks and speech, making the commute and office work more bearable.Apple’s class-leading transparency mode is just as good on the new earbuds, sounding natural as if you weren’t actually wearing the earbuds. It makes using them as hearing aids or out on the street with some dampening of sudden loud sounds very good indeed.Call quality is first-rate, and my voice sounded clear and natural in quiet or noisy environments with only a hint of road noise from some loud streets audible on the call.SustainabilityThe case charges via USB-C, MagSafe, Qi or Apple Watch charger, and has a new feature to limit charging of the earbuds to prolong their battery health. Photograph: Samuel Gibbs/The GuardianApple does not provide an expected lifespan for the batteries. Those in similar devices typically maintain at least 80% of their original capacity for 500 full charge cycles. The earbuds are not repairable, but Apple offers a battery service for £49 per earbud or case and offers replacements for those lost or damaged costing from £79 an item. The repair specialists iFixit rated the earbuds zero out of 10 for repairability.The AirPods and case contain 40% recycled material by weight including aluminium, cobalt, copper, gold, lithium, plastic, rare earth elements and tin. Apple offers trade-in and free recycling schemes and breaks down the environmental impact of the earbuds in its report.PriceThe AirPods Pro 3 cost £219 (€249/$249/A$429).For comparison, the AirPods 4 start at £119, the Beats Powerbeats Pro 2 cost £250, the Sennheiser Momentum TW4 cost £199, the Google Pixel Buds Pro 2 cost £219, the Sony WF-1000XM5 cost £219 and the Bose QuietComfort Ultra earbuds cost £300.VerdictThe AirPods Pro 3 take what was great about the ubiquitous second-generation models and improves almost everything.Longer battery life and a better, more comfortable fit for extended listening sessions are very welcome, as is the bigger, wider sound. Proper water resistance and built-in heart rate monitoring makes them useful for workouts, particularly those such as powerlifting that make wearing a watch difficult. The live translation feature worked better than expected, but has limitations that make it less useful for real-life conversations.The best bit is very effective noise cancelling that rivals some of the greatest over-ear headphones, but in a tiny set of earbuds that are much easier to carry around.Audiophiles will find they sound a little too clinical. While they work with any Bluetooth device, including Android phones, PCs and games consoles, they require an iPhone, iPad or Mac for full functionality. But the biggest letdown remains repairability, which remains a problem for most true wireless earbuds and loses them a star. Pros: very effective noise cancelling, great sound, best-in-class transparency, water resistance, built-in HR monitoring, great controls, advanced features with Apple devices including spatial audio, very comfortable, excellent case, top class call quality. Cons: extremely difficult to repair, expensive, no hi-res audio support, lack features when connected to Android/Windows, look the same as predecessors, only available in white. The AirPods Pro 3 are some of the very best earbuds you can buy, particularly if you use an iPhone. Photograph: Samuel Gibbs/The Guardian

If You Want to Stay Healthy and Care About Humanity, Here’s What to Eat

This story was originally published by Guardian and is reproduced here as part of the Climate Desk collaboration. Adoption of a plant-rich “planetary health diet” could prevent 40,000 early deaths a day across the world, according to a landmark report. The diet—which allows moderate meat consumption—and related measures would also slash the food-related emissions driving global heating by […]

This story was originally published by Guardian and is reproduced here as part of the Climate Desk collaboration. Adoption of a plant-rich “planetary health diet” could prevent 40,000 early deaths a day across the world, according to a landmark report. The diet—which allows moderate meat consumption—and related measures would also slash the food-related emissions driving global heating by half by 2050. Today, a third of greenhouse gas emissions come from the global food system and taming the climate crisis is impossible without changing how the world eats, the researchers said. Food production is also the biggest cause of the destruction of wildlife and forests and the pollution of water. The planetary health diet (PHD) sets out how the world can simultaneously improve the health of people and the planet, and provide enough food for an expected global population of 9.6 billion people by 2050. “This is not a deprivation diet…” It “could be delicious, aspirational and healthy.” The diet is flexible, allowing it to be adapted to local tastes, and can include some animal products or be vegetarian or vegan. However, all versions advise eating more vegetables, fruits, nuts, legumes and whole grains than most people in the world currently eat. In many places, today’s diets are unhealthy and unsustainable due to too much meat, milk and cheese, animal fats and sugar. People in the US and Canada eat more than seven times the PHD’s recommended amount of red meat, while it is five times more in Europe and Latin America, and four times more in China. However, in some regions where people’s diets are heavily reliant on starchy foods, such as sub-Saharan Africa, a small increase in chicken, dairy and eggs would be beneficial to health, the report found. North American adult diets in 2020 versus planetary health recommendation, daily per capita intake in grammesGuardian Severe inequalities in the food system must also be ended to achieve healthy and sustainable diets, the researchers said. The wealthiest 30 percent of the world’s population generates more than 70 percent of food-related environmental damage, it found. Furthermore, 2.8 billion people cannot afford a healthy diet and 1 billion are undernourished, despite enough food being produced globally. The food system is also failing the 1 billion people living with obesity, the report said. The report recommends shifting taxes to make unhealthy food more costly and healthy food cheaper, regulating the advertising of unhealthy food and using warning labels, and the shifting of today’s massive agricultural subsidies to healthier and more sustainable foods. “What we put on our plates can save millions of lives, cut billions of tonnes of emissions, halt the loss of biodiversity, and create a fairer food system,” said Prof Johan Rockström, who co-chaired the EAT-Lancet Commission that produced the report. “The evidence is undeniable: transforming food systems is not only possible, it’s essential to securing a safe, just, and sustainable future for all.” “This is not a deprivation diet,” said Prof Walter Willett of the Harvard TH Chan school of public health, and another commission co-chair. “This is something that could be delicious, aspirational and healthy. It also allows for cultural diversity and individual preferences, providing flexibility.” “Our recommendations are grounded in scientific evidence and real-world experience.” The report, published in the Lancet, was produced by 70 leading experts from 35 countries and six continents. It builds on the 2019 report that introduced the PHD, but includes new evidence of the health benefits of the diet. “We have been able to look at this diet in relation to health outcomes such as total mortality, diabetes, respiratory diseases, heart disease, stroke, etc and we found very strong inverse relationships” said Willett. The diet was also linked to reduced cancer and neurodegenerative diseases. Overall, the researchers estimated global adoption of the PHD could prevent 15m early deaths a year in adults. The estimate did not include the impact of the diet reducing obesity, meaning it is probably an underestimate. The PHD recommends plant-rich, flexible diets, including: Fruits and vegetables—at least five portions a day Whole grains—three to four portions a day Nuts—one portion per day Legumes (beans, peas, lentils)—one portion per day Dairy—one serving of milk, yoghurt or cheese portions a day Eggs —three to four a week Chicken—two portions a week Fish—two portions a week Red meat—one portion a week Marco Springmann from UCL in the UK and an author of the report said the differences between the PHD and current diets vary: “What needs to be reduced differs a lot. In low income countries, it’s the starchy foods and grains, whereas in high income countries it is animal-sourced foods, sugar, saturated fats, and dairy. It’s insane how much dairy is consumed in Europe and North America.” The data underlying the report is available online and can be used to tailor different planetary health diets for the tastes of people in specific countries and of different ages. The website also shows how much the diets reduce deaths, improve nutrition, and cut environmental impacts. “Hopefully this will lead to more science-based policymaking,” said Springmann. The PHD is better than current average diets for many nutrients, including fatty acids, fibre, folate, magnesium and zinc. Adequate iron and vitamin B12 could be provided by green leafy vegetables, fermented soy foods and algae, the researchers said. Moving diets towards the PHD could be achieved by helping consumers make better everyday choices, said Line Gordon, director of the Stockholm Resilience Centre, for example by shifting taxes to make healthy foods cheaper, and putting warning labels on unhealthy foods. “But it is not just about getting prices lower, it’s also about bringing purchasing power up so that people can afford a healthier diet” she said. “Our recommendations are grounded in scientific evidence and real-world experience,” Gordon said. “Changes are already under way, from school meal programmes to regenerative agriculture and food waste reduction initiatives.” England banned price promotions on unhealthy foods on Wednesday and will ban advertising such foods online. The report estimates that food-related ill health and environmental damage costs society about $15 trillion a year. It said investments to transform the food system would cost $200 billion to $500 billion a year, but save $5 trillion. Alongside a shift in diets, the report calls for other changes to the food system, including cutting the loss and waste of food, greener farming practices, and decent working conditions, as a third of food workers earn below living wages. The launch of the PHD in 2019 led to attacks from meat industry interests. Rockström said: “The [new report] is a landmark achievement. It is a state-of-the-art scientific assessment that quantifies healthy diets for all human beings in the world and the environmental boundaries all food systems need to meet to stay safe. So we have a really rigorous foundation for our [results]. We are ready to meet that assault.”

Seasonal Allergies Might Increase Suicide Rate, Study Says

By Dennis Thompson HealthDay ReporterMONDAY, Oct. 6, 2025 (HealthDay News) — Seasonal allergies are considered an annoyance to most, and maddening...

By Dennis Thompson HealthDay ReporterMONDAY, Oct. 6, 2025 (HealthDay News) — Seasonal allergies are considered an annoyance to most, and maddening to some.Few think of seasonal sniffles and sneezes as potentially fatal — but we might be overlooking the danger they pose, a new study warns.High pollen counts are linked to a significant increase in suicide risk, according to findings published in the December issue of the Journal of Health Economics as the U.S. enters fall allergy season.Further, suicide risk increases as airborne levels of pollen rise, researchers found.The physical misery caused by seasonal allergies likely contributes to this increase, by wrecking people’s sleep and increasing mental distress, researchers speculated."During our study period, there were nearly 500,000 suicides in the U.S.," said lead researcher Joelle Abramowitz, an associate research scientist at the University of Michigan’s Institute for Social Research."Based on our incremental data, we estimate that pollen may have been a contributing factor in up to 12,000 of those deaths over the period, or roughly 900 to 1,200 deaths per year,” she said in a news release.For the study, researchers compared suicides reported between 2006 and 2018 with daily pollen counts from 186 counties in 34 metropolitan areas across the United States.Results showed an association between suicide and pollen counts that increases in strength, after the research team divided pollen levels into four tiers.Suicide risk jumped 7.4% at the worst pollen counts; 5.5% higher at the third-highest level; and 4.5% at the second level, all compared to the lowest level of airborne pollen.People with known mental health problems were more vulnerable, experiencing a nearly 9% increase in their risk of suicide on days with the highest pollen counts, results showed.“A small shock could have a big effect if you're already in a vulnerable state," Abramowitz said.The results indicate that seasonal allergies should be taken more seriously, and not seen as a mere nuisance, researchers said.More accurate pollen forecasting and better public communication on the mental health impact of seasonal allergies could save lives, by providing people the opportunity to protect themselves, researchers said.This will become even more important as climate change progresses, extending and intensifying pollen seasons, researchers said."We should be more conscious of our responsiveness to small environmental changes, such as pollen, and our mental health in general," Abramowitz said."Given our findings, I believe medical providers should be aware of a patient's allergy history, as other research has also established a connection between allergies and a higher risk for suicide,” she added. “I hope this research can lead to more tailored care and, ultimately, save lives."SOURCE: University of Michigan, news release, Sept. 29, 2025Copyright © 2025 HealthDay. All rights reserved.

Chemists create red fluorescent dyes that may enable clearer biomedical imaging

The new dyes are based on boron-containing molecules that were previously too unstable for practical use.

MIT chemists have designed a new type of fluorescent molecule that they hope could be used for applications such as generating clearer images of tumors.The new dye is based on a borenium ion — a positively charged form of boron that can emit light in the red to near-infrared range. Until recently, these ions have been too unstable to be used for imaging or other biomedical applications.In a study appearing today in Nature Chemistry, the researchers showed that they could stabilize borenium ions by attaching them to a ligand. This approach allowed them to create borenium-containing films, powders, and crystals, all of which emit and absorb light in the red and near-infrared range.That is important because near-IR light is easier to see when imaging structures deep within tissues, which could allow for clearer images of tumors and other structures in the body.“One of the reasons why we focus on red to near-IR is because those types of dyes penetrate the body and tissue much better than light in the UV and visible range. Stability and brightness of those red dyes are the challenges that we tried to overcome in this study,” says Robert Gilliard, the Novartis Professor of Chemistry at MIT and the senior author of the study.MIT research scientist Chun-Lin Deng is the lead author of the paper. Other authors include Bi Youan (Eric) Tra PhD ’25, former visiting graduate student Xibao Zhang, and graduate student Chonghe Zhang.Stabilized boreniumMost fluorescent imaging relies on dyes that emit blue or green light. Those imaging agents work well in cells, but they are not as useful in tissue because low levels of blue and green fluorescence produced by the body interfere with the signal. Blue and green light also scatters in tissue, limiting how deeply it can penetrate.Imaging agents that emit red fluorescence can produce clearer images, but most red dyes are inherently unstable and don’t produce a bright signal, because of their low quantum yields (the ratio of fluorescent photons emitted per photon of light is absorbed). For many red dyes, the quantum yield is only about 1 percent.Among the molecules that can emit near-infrared light are borenium cations —positively charged ions containing an atom of boron attached to three other atoms.When these molecules were first discovered in the mid-1980s, they were considered “laboratory curiosities,” Gilliard says. These molecules were so unstable that they had to be handled in a sealed container called a glovebox to protect them from exposure to air, which can lead them to break down.Later, chemists realized they could make these ions more stable by attaching them to molecules called ligands. Working with these more stable ions, Gillliard’s lab discovered in 2019 that they had some unusual properties: Namely, they could respond to changes in temperature by emitting different colors of light.However, at that point, “there was a substantial problem in that they were still too reactive to be handled in open air,” Gilliard says.His lab began working on new ways to further stabilize them using ligands known as carbodicarbenes (CDCs), which they reported in a 2022 study. Due to this stabilization, the compounds can now be studied and handled without using a glovebox. They are also resistant to being broken down by light, unlike many previous borenium-based compounds.In the new study, Gilliard began experimenting with the anions (negatively charged ions) that are a part of the CDC-borenium compounds. Interactions between these anions and the borenium cation generate a phenomenon known as exciton coupling, the researchers discovered. This coupling, they found, shifted the molecules’ emission and absorption properties toward the infrared end of the color spectrum. These molecules also generated a high quantum yield, allowing them to shine more brightly.“Not only are we in the correct region, but the efficiency of the molecules is also very suitable,” Gilliard says. “We’re up to percentages in the thirties for the quantum yields in the red region, which is considered to be high for that region of the electromagnetic spectrum.”Potential applicationsThe researchers also showed that they could convert their borenium-containing compounds into several different states, including solid crystals, films, powders, and colloidal suspensions.For biomedical imaging, Gilliard envisions that these borenium-containing materials could be encapsulated in polymers, allowing them to be injected into the body to use as an imaging dye. As a first step, his lab plans to work with researchers in the chemistry department at MIT and at the Broad Institute of MIT and Harvard to explore the potential of imaging these materials within cells.Because of their temperature responsiveness, these materials could also be deployed as temperature sensors, for example, to monitor whether drugs or vaccines have been exposed to temperatures that are too high or low during shipping.“For any type of application where temperature tracking is important, these types of ‘molecular thermometers’ can be very useful,” Gilliard says.If incorporated into thin films, these molecules could also be useful as organic light-emitting diodes (OLEDs), particularly in new types of materials such as flexible screens, Gilliard says.“The very high quantum yields achieved in the near-IR, combined with the excellent environmental stability, make this class of compounds extremely interesting for biological applications,” says Frieder Jaekle, a professor of chemistry at Rutgers University, who was not involved in the study. “Besides the obvious utility in bioimaging, the strong and tunable near-IR emission also makes these new fluorophores very appealing as smart materials for anticounterfeiting, sensors, switches, and advanced optoelectronic devices.”In addition to exploring possible applications for these dyes, the researchers are now working on extending their color emission further into the near-infrared region, which they hope to achieve by incorporating additional boron atoms. Those extra boron atoms could make the molecules less stable, so the researchers are also working on new types of carbodicarbenes to help stabilize them.The research was funded by the Arnold and Mabel Beckman Foundation and the National Institutes of Health.

Join us to forge
a sustainable future

Our team is always growing.
Become a partner, volunteer, sponsor, or intern today.
Let us know how you would like to get involved!

CONTACT US

sign up for our mailing list to stay informed on the latest films and environmental headlines.

Subscribers receive a free day pass for streaming Cinema Verde.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.