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What Time Do You Eat? Recent Research Reveals That It Can Impact Your Overall Health

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Saturday, July 20, 2024

Recent research in chrononutrition reveals that meal timing can significantly affect health outcomes. Intermittent fasting regimens offer a simplified dietary approach that can enhance weight management and overall health without the burden of calorie counting, particularly benefiting those with limited resources.A special issue of the Journal of the Academy of Nutrition and Dietetics on chrononutrition clarifies the science behind the effectiveness of fasting regimes.Recent research explores how aligning meal times with our biological clocks can improve health, focusing on intermittent fasting’s role in weight management and metabolic health without the need for calorie counting.Accumulating research on the timing of meals in relation to our circadian rhythms and metabolism suggests that the timing of our food intake could impact our health and well-being. A special issue of the Journal of the Academy of Nutrition and Dietetics (JAND) on chrononutrition, published by Elsevier, examines the effects of various fasting regimens and covers safety considerations and practical guidance.The field of chrononutrition is gaining traction as it explores the relationship between temporal eating patterns, circadian rhythms, and metabolism for optimal health. Guest Editor Krista Varady, PhD, Department of Kinesiology and Nutrition, University of Illinois Chicago, specializes in studying the efficacy of intermittent fasting for weight loss, weight management, and lowering the risk of metabolic diseases in obese adults. With more than 15 years of research experience, she is recognized as one of the top researchers in this field.Dr. Varady says, “Intermittent fasting has emerged as one of the most popular diets for weight loss in recent years. The diet can be defined, in basic terms, as periods of eating, alternated with periods of not eating. This special issue examines the effects of various fasting regimens, such as time-restricted eating, alternate-day fasting, and the 5:2 diet, on body weight, cardiometabolic disease risk, and sleep and exercise performance in human subjects. Pertinent safety considerations and practical guidance on applying the diets are also covered.”Clinical Implications and StudiesEditor-in-Chief of JAND, Linda G. Snetselaar, PhD, RDN, FAND, LD, a professor in the Department of Epidemiology at the University of Iowa, adds, “The findings presented in this special issue have important clinical implications. I believe the timing of eating will become increasingly important as we address dietary interventions related to chronic disease risk factors.”The special issue includes the novel study “Randomized Controlled Feasibility Trial of Late 8-Hour Time-Restricted Eating for Adolescents With Type 2 Diabetes,” in which researchers examine the feasibility of eating within an 8-hour window as an interventional strategy for weight loss and glucose management among adolescents diagnosed with obesity and new-onset type 2 diabetes, compared with a prolonged eating window.Lead investigator Alaina P. Vidmar, MD, Children’s Hospital Los Angeles and Keck School of Medicine of USC, explains, “The prevalence of type 2 diabetes in adolescents is steadily increasing, specifically among historically marginalized communities. Many adolescents prefer to go to bed later and sleep in later, so an early eating window may not align with developmental and social schedules that often shift their food consumption to later in the day. We trialed a late eating window for our cohort and found that late time-restricted eating is safe and acceptable for this subset of adolescents as it can result in clinically meaningful weight loss, reduction in alanine transaminase, and significant caloric reduction; it did not negatively impact sleep, eating behaviors, or physical activity.”Sleep and Eating PatternsAnother paper, “Indices of Sleep Health Are Associated With Timing and Duration of Eating in Young Adults,” details findings from a cross-sectional study among 52 young adults without chronic diseases or conditions on whether timing and/or duration of eating behaviors throughout the day affect sleep health.Lead investigator Jess A. Gwin, PhD, Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine, says, “Breakfast skipping and nighttime eating are among typical eating behaviors observed in young adults in the United States. Our study found that the timing of eating was associated with sleep-wake onset and sleep efficiency. This highlights the need for additional studies to understand whether manipulating the timing of eating occasions to better align with sleep-wake cycles could improve sleep health.”Interventions tailored to individuals’ preferences and circumstances may benefit time-restricted eating adherence, according to the article “Time-Restricted Eating in Community-Dwelling Adults: Correlates of Adherence and Discontinuation in a Cross-Sectional Online Survey Study.” Leader of the research team Sydney G. O’Connor, PhD, Office of Behavioral and Social Sciences Research, National Institutes of Health, notes, “Dietary adherence is the strongest predictor of successful weight loss and maintenance; therefore, identifying dietary strategies that facilitate adherence is a priority in the field of behavioral weight management. We looked at motivators such as weight maintenance, health (not weight), improved sleep, disease prevention, and drivers such as the ability to work from home and the impact of COVID-19.”Dr. Varady concludes, “Many people stop adhering to standard diets that restrict calories because they become frustrated with having to regularly monitor food intake day in and day out. Intermittent fasting protocols can bypass this requirement by allowing participants to simply ‘watch the clock’ instead of monitoring calories, while still producing weight loss. Furthermore, intermittent fasting does not require the purchase of expensive food products and allows individuals to continue consuming familiar foods, making it a highly accessible diet, especially for lower-resource patient groups. Although fasting regimens are no more effective than other diet interventions for weight management, these protocols offer individuals an alternative, straightforward approach to addressing obesity by omitting the need for calorie counting. While weight loss is important, having a diet with a wide variety of nutrient-dense foods such as fruits, vegetables, and legumes is paramount in maintaining a replete nutritional status. These foods can be both inexpensive and culturally appropriate.”References:“Randomized Controlled Feasibility Trial of Late 8-Hour Time-Restricted Eating for Adolescents With Type 2 Diabetes” by Elizabeth Hegedus, My H. Vu, Sarah Jeanne Salvy, Jomanah Bakhsh, Michael I. Goran, Jennifer K. Raymond, Juan C. Espinoza and Alaina P. Vidmar, 30 October 2023, Journal of the Academy of Nutrition and Dietetics.DOI: 10.1016/j.jand.2023.10.012“Indices of Sleep Health Are Associated With Timing and Duration of Eating in Young Adults” by Charlotte A. Griffith, Heather J. Leidy and Jess A. Gwin, 30 April 2024, Journal of the Academy of Nutrition and Dietetics.DOI: 10.1016/j.jand.2024.04.016“Time-Restricted Eating in Community-Dwelling Adults: Correlates of Adherence and Discontinuation in a Cross-Sectional Online Survey Study” by Caitlin P. Bailey, Patrick Boyd, Marissa M. Shams-White, Susan M. Czajkowski, Linda Nebeling, Jill Reedy and Sydney G. O’Connor, 16 December 2023, Journal of the Academy of Nutrition and Dietetics.DOI: 10.1016/j.jand.2023.12.006

A special issue of the Journal of the Academy of Nutrition and Dietetics on chrononutrition clarifies the science behind the effectiveness of fasting regimes. Recent...

Intermittent Fasting Concept

Recent research in chrononutrition reveals that meal timing can significantly affect health outcomes. Intermittent fasting regimens offer a simplified dietary approach that can enhance weight management and overall health without the burden of calorie counting, particularly benefiting those with limited resources.

A special issue of the Journal of the Academy of Nutrition and Dietetics on chrononutrition clarifies the science behind the effectiveness of fasting regimes.

Recent research explores how aligning meal times with our biological clocks can improve health, focusing on intermittent fasting’s role in weight management and metabolic health without the need for calorie counting.

Accumulating research on the timing of meals in relation to our circadian rhythms and metabolism suggests that the timing of our food intake could impact our health and well-being. A special issue of the Journal of the Academy of Nutrition and Dietetics (JAND) on chrononutrition, published by Elsevier, examines the effects of various fasting regimens and covers safety considerations and practical guidance.

The field of chrononutrition is gaining traction as it explores the relationship between temporal eating patterns, circadian rhythms, and metabolism for optimal health.

Guest Editor Krista Varady, PhD, Department of Kinesiology and Nutrition, University of Illinois Chicago, specializes in studying the efficacy of intermittent fasting for weight loss, weight management, and lowering the risk of metabolic diseases in obese adults. With more than 15 years of research experience, she is recognized as one of the top researchers in this field.

Dr. Varady says, “Intermittent fasting has emerged as one of the most popular diets for weight loss in recent years. The diet can be defined, in basic terms, as periods of eating, alternated with periods of not eating. This special issue examines the effects of various fasting regimens, such as time-restricted eating, alternate-day fasting, and the 5:2 diet, on body weight, cardiometabolic disease risk, and sleep and exercise performance in human subjects. Pertinent safety considerations and practical guidance on applying the diets are also covered.”

Clinical Implications and Studies

Editor-in-Chief of JAND, Linda G. Snetselaar, PhD, RDN, FAND, LD, a professor in the Department of Epidemiology at the University of Iowa, adds, “The findings presented in this special issue have important clinical implications. I believe the timing of eating will become increasingly important as we address dietary interventions related to chronic disease risk factors.”

The special issue includes the novel study “Randomized Controlled Feasibility Trial of Late 8-Hour Time-Restricted Eating for Adolescents With Type 2 Diabetes,” in which researchers examine the feasibility of eating within an 8-hour window as an interventional strategy for weight loss and glucose management among adolescents diagnosed with obesity and new-onset type 2 diabetes, compared with a prolonged eating window.

Lead investigator Alaina P. Vidmar, MD, Children’s Hospital Los Angeles and Keck School of Medicine of USC, explains, “The prevalence of type 2 diabetes in adolescents is steadily increasing, specifically among historically marginalized communities. Many adolescents prefer to go to bed later and sleep in later, so an early eating window may not align with developmental and social schedules that often shift their food consumption to later in the day. We trialed a late eating window for our cohort and found that late time-restricted eating is safe and acceptable for this subset of adolescents as it can result in clinically meaningful weight loss, reduction in alanine transaminase, and significant caloric reduction; it did not negatively impact sleep, eating behaviors, or physical activity.”

Sleep and Eating Patterns

Another paper, “Indices of Sleep Health Are Associated With Timing and Duration of Eating in Young Adults,” details findings from a cross-sectional study among 52 young adults without chronic diseases or conditions on whether timing and/or duration of eating behaviors throughout the day affect sleep health.

Lead investigator Jess A. Gwin, PhD, Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine, says, “Breakfast skipping and nighttime eating are among typical eating behaviors observed in young adults in the United States. Our study found that the timing of eating was associated with sleep-wake onset and sleep efficiency. This highlights the need for additional studies to understand whether manipulating the timing of eating occasions to better align with sleep-wake cycles could improve sleep health.”

Interventions tailored to individuals’ preferences and circumstances may benefit time-restricted eating adherence, according to the article “Time-Restricted Eating in Community-Dwelling Adults: Correlates of Adherence and Discontinuation in a Cross-Sectional Online Survey Study.” Leader of the research team Sydney G. O’Connor, PhD, Office of Behavioral and Social Sciences Research, National Institutes of Health, notes, “Dietary adherence is the strongest predictor of successful weight loss and maintenance; therefore, identifying dietary strategies that facilitate adherence is a priority in the field of behavioral weight management. We looked at motivators such as weight maintenance, health (not weight), improved sleep, disease prevention, and drivers such as the ability to work from home and the impact of COVID-19.”

Dr. Varady concludes, “Many people stop adhering to standard diets that restrict calories because they become frustrated with having to regularly monitor food intake day in and day out. Intermittent fasting protocols can bypass this requirement by allowing participants to simply ‘watch the clock’ instead of monitoring calories, while still producing weight loss. Furthermore, intermittent fasting does not require the purchase of expensive food products and allows individuals to continue consuming familiar foods, making it a highly accessible diet, especially for lower-resource patient groups. Although fasting regimens are no more effective than other diet interventions for weight management, these protocols offer individuals an alternative, straightforward approach to addressing obesity by omitting the need for calorie counting. While weight loss is important, having a diet with a wide variety of nutrient-dense foods such as fruits, vegetables, and legumes is paramount in maintaining a replete nutritional status. These foods can be both inexpensive and culturally appropriate.”

References:

“Randomized Controlled Feasibility Trial of Late 8-Hour Time-Restricted Eating for Adolescents With Type 2 Diabetes” by Elizabeth Hegedus, My H. Vu, Sarah Jeanne Salvy, Jomanah Bakhsh, Michael I. Goran, Jennifer K. Raymond, Juan C. Espinoza and Alaina P. Vidmar, 30 October 2023, Journal of the Academy of Nutrition and Dietetics.
DOI: 10.1016/j.jand.2023.10.012

“Indices of Sleep Health Are Associated With Timing and Duration of Eating in Young Adults” by Charlotte A. Griffith, Heather J. Leidy and Jess A. Gwin, 30 April 2024, Journal of the Academy of Nutrition and Dietetics.
DOI: 10.1016/j.jand.2024.04.016

“Time-Restricted Eating in Community-Dwelling Adults: Correlates of Adherence and Discontinuation in a Cross-Sectional Online Survey Study” by Caitlin P. Bailey, Patrick Boyd, Marissa M. Shams-White, Susan M. Czajkowski, Linda Nebeling, Jill Reedy and Sydney G. O’Connor, 16 December 2023, Journal of the Academy of Nutrition and Dietetics.
DOI: 10.1016/j.jand.2023.12.006

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Mapping the Exposome: Science Broadens Focus to Environmental Disease Triggers

By Deanna Neff HealthDay ReporterSATURDAY, Nov. 29, 2025 (HealthDay News) — After decades of intense focus on genetics, the biomedical research...

By Deanna Neff HealthDay ReporterSATURDAY, Nov. 29, 2025 (HealthDay News) — After decades of intense focus on genetics, the biomedical research community is undergoing a major shift, focusing on a new framework called "exposomics."Similar to the way scientists work to map the human genome, this emerging field aims to map the chemical, physical, social and biological elements a person encounters throughout their life.Experts estimate that genetic mutations account for only about 10% of diseases like Parkinson’s for example. The remaining 90% are thought to be caused by environmental factors, prompting scientists to look beyond genes, the Association of American Medical Colleges (AAMC) reported.Some examples of exposomic data include light and temperature, biomarkers in the blood or other body fluids, dietary intake, environmental chemicals, physical activity, income and education.The ultimate goal? To turn this big bucket of individual knowledge points into practical, personalized health solutions.Researchers envision a future where a person's "exposomic profile" is included in their electronic medical records, according to the AAMC.Gary Miller, vice dean for research strategy and innovation at the Columbia University Mailman School of Public Health in New York City, who helped coin the term two decades ago, says the field is now gaining momentum.Exposomics is an enormous undertaking because it requires researchers from various disciplines — including genetics, environmental science and data science — to work together.The goal is to move beyond simply identifying a single cause of disease and instead capture the entire picture of a person’s unique lifetime of exposures.Driving this surge are new technologies that can handle the sheer volume of data involved to map all of the possible exposures.Geospatial data: Satellite images and social determinants of health data help to measure location-specific exposures like air pollution and water quality. Mass spectrometry: Advanced chemical analysis helps to detect thousands of markers in biological samples like blood and urine. Wearable devices: Devices, such as the "exposometer" developed at Stanford Medicine in California, can collect chemical and biological samples directly from the wearer. Chirag Patel, an associate professor at Harvard Medical School and co-leader of NEXUS, explained that his lab uses computational models and artifical intelligence to systematically sort through huge amounts of data.“We’re moving away from looking at causes for disease in a targeted fashion... and moving toward what are non-targeted mass spectrometry approaches,” Patel told AAMC.Rima Habre, also co-leader of NEXUS and associate professor of environmental health and spatial sciences at the University of Southern California Keck School of Medicine, believes exposomics can help physicians move beyond educated guesswork.She says it's more "discovery-based." It allows researchers to scan everything and follow it up with hypothesis testing.As Miller notes, this new health assessment paradigm requires both sides of the coin: “The genomics and exposomics. They complement each other.”SOURCE: Association of American Medical Colleges (AAMC), Nov. 12, 2025Copyright © 2025 HealthDay. All rights reserved.

Some Suicide Victims Show No Typical Warning Signs, Study Finds

By I. Edwards HealthDay ReporterWEDNESDAY, Nov. 26, 2025 (HealthDay News) — For many families who lose someone to suicide, the same question comes...

WEDNESDAY, Nov. 26, 2025 (HealthDay News) — For many families who lose someone to suicide, the same question comes up again and again: “How did we not see this coming?”A new study suggests that for some people, there truly weren’t clear warning signs to see.Researchers at the University of Utah found that people who die by suicide without showing prior warning signs, such as suicidal thoughts or past attempts, may have different underlying risk factors than those who express suicidal behavior.About half of people who die by suicide have no known history of suicidal thoughts or behaviors. Many also don't have diagnosed mental health conditions like depression.To better understand these people, researchers analyzed anonymized genetic data from more than 2,700 people who died by suicide.They found that people with no prior signs of suicide had:"There are a lot of people out there who may be at risk of suicide where it’s not just that you’ve missed that they’re depressed, it’s likely that they’re in fact actually not depressed," lead study author Hilary Coon, a psychiatry professor at the University of Utah in Salt Lake City, said in a news release."That is important in widening our view of who may be at risk," she added. "We need to start to think about aspects leading to risk in different ways."The study also found that this group wasn't any more likely than the general population to show traits like chronic low mood or neuroticism.Suicide prevention has long focused on identifying and treating depression and related mental health disorders. But this research suggests that approach may not reach everyone who's at risk."A tenet in suicide prevention has been that we just need to screen people better for associated conditions like depression," Coon explained."And if people had the same sort of underlying vulnerabilities, then additional efforts in screening might be very helpful. But for those who actually have different underlying vulnerabilities, then increasing that screening might not help for them."In other words: If someone isn’t depressed or showing typical symptoms, current screening tools may miss them.Coon and her team are now looking into other factors that might raise suicide risk in this hidden group, including chronic pain, inflammation and respiratory diseases.They are also studying traits that may protect against suicide to better understand why some people remain resilient even in difficult situations.She emphasized that there is no single suicide "gene."Her goal? To help doctors spot high-risk individuals earlier, even when they do not express suicidal thoughts."If people have a certain type of clinical diagnosis that makes them particularly vulnerable within particular environmental contexts, they still may not ever say they’re suicidal," Coon said. "We hope our work may help reveal traits and contexts associated with high risk so that doctors can deliver care more effectively and specifically."The 988 Lifeline is available for anyone facing mental health struggles, emotional distress, alcohol or drug use concerns or who just needs someone to talk to.SOURCE: University of Utah Health, news release, Nov. 24, 2025Copyright © 2025 HealthDay. All rights reserved.

Switch to Vegan Diet Could Cut Your Greenhouse Gas Emissions in Half

By Ernie Mundell HealthDay ReporterWEDNESDAY, Nov. 26, 2025 (HealthDay News) — The equivalent of a 4.3-mile trip in a gas-powered car: That’s the...

By Ernie Mundell HealthDay ReporterWEDNESDAY, Nov. 26, 2025 (HealthDay News) — The equivalent of a 4.3-mile trip in a gas-powered car: That’s the amount of greenhouse gas emissions the average person spares the planet each day when they switch to a healthy, low-fat vegan diet, new research shows.The group describes itself as “a nonprofit organization that promotes preventive medicine.” It has long advocated for plant-based diets as being healthier for people and the planet. The new data comes out of prior Physicians Committee research that found that low-fat plant-based diets are effective in helping people shed excess pounds and help control blood sugar, as compared to fattier diets containing meat.  Kahleova’s new analysis looked at the environmental impact of switching to a vegan diet. They linked data from two datasets — the U.S. Department of Agriculture’s Food Commodity Intake Database and the Database of Food Impacts on the Environment for Linking to Diets.The analysis found a 51% daily reduction in personal greenhouse gas emissions (GHGE) once a person made the switch — the daily equivalent of preventing carbon dioxide emissions from a more than 4-mile gas engine car trip. As well, switching to the vegan diet spurred a 51% decline in what’s known as cumulative energy demand (CED) — the amount of energy used up in harvesting the raw materials consumed in a diet, as well as their processing, transport and disposal.Much of these reductions were linked to folks forgoing meat, dairy products and eggs, the research showed.According to Kahleova, plant-based diets are gaining popularity in the United States, with a recent survey showing that almost half of Americans take environmental concerns into account when thinking about switching away from meat.“As awareness of its environmental impact grows, swapping plant foods for animal products will be as ubiquitous as reduce, reuse and recycle,” she said. “Prior research has shown that red meat, in particular, has an outsized impact on energy use compared to grains, legumes, fruits and vegetables,” Kahleova added. “Our randomized study shows just how much a low-fat vegan diet is associated with a substantial reduction in greenhouse gas emissions and energy use, significant drivers of climate change.”SOURCE: Physicians Committee for Responsible Medicine, news release, Nov. 17, 2025Copyright © 2025 HealthDay. All rights reserved.

These 5-Second Hand Exercises For Dementia Are Going Viral. Here's What Neurologists Think.

Is boosting your brain health really this simple?

Social media is full of health hacks for better sleep, clear skin, a functioning gut, you name it. Lately, a tip for aging and cognitive function is gaining traction. Videos showing hand and finger exercises have racked up millions of views on TikTok and Instagram, with users suggesting these movements can help prevent dementia or Alzheimer’s disease.The exercises include things like alternated clapping, tapping, arm circles and pointing your fingers in different directions. And although they might look easy enough, exasperated folks in the comments sections highlight that some of these motions are a lot harder than they appear. But does failing at intricate finger movements and hand coordination exercises mean you’re cognitively doomed? And can these exercises really ― as the captions claim ― prevent dementia or Alzheimer’s? HuffPost asked a neurologist to weigh in. “While there are a few studies showing that aspects of mild cognitive impairment might be improved with these types of hand exercises, I would put forward that there is nothing magical about these movements,” said neurologist Dr. Chris Winter.Hand exercises are a way to practice motor skills, which can be beneficial for maintaining cognitive abilities as we age. But it might be a stretch to suggest that specific movements are going to remove your risk of developing dementia or Alzheimer’s disease. Can simple hand exercises really prevent dementia?Winter explained that hand and finger coordination can be beneficial as part of a larger pattern of mental and physical activity, but it’s not the hand gestures themselves that matter ― it’s the engagement and concentration involved.“Learning to play the piano or other activities that force concentration and the practice of improved hand/eye coordination are potentially just as useful,” Winter said. “I recommend that people stay active and engage in appropriately challenging activities. Learn a new language, pick up a guitar or a used set of drums, play pickleball. If you have the capacity to do these things, get off of TikTok and go do these things instead.”Brain function is less about hand gestures and more about movement and mental engagement that challenge your mind and body overall. “While no single exercise can prevent Alzheimer’s disease, regularly engaging your brain in complex, novel activities helps build what we call ‘brain reserve.’ A higher brain reserve can delay the onset of dementia symptoms or reduce their severity later in life,” said Dr. Majid Fotuhi, a neurologist and author of “The Invincible Brain: The Clinically Proven Plan to Age-Proof Your Brain and Stay Sharp for Life.”Board-certified neurologist Dr. Luke K. Barr emphasized that TikTok viewers shouldn’t mistake their inability to do some of these hand exercises as a red flag for cognitive decline. If you have trouble alternating pointing your thumbs and pinkies, that doesn’t mean you’re “already developing dementia,” as some commenters fear. “These are complex exercises that are difficult, especially at first, and require a lot of concentration and practice,” Barr said. “Just because someone is not able to do it easily right away, does not necessarily mean that they have dementia.”As with most anything complicated, practice makes perfect. “I think there are a variety of reasons why one could not do these gestures ― or rub their stomach while patting their head,” Winter added. “While someone with significant dementia is probably not likely to be able to do these activities, the fact that someone struggles with coordination does not indicate dementia or progression in this direction. Ability to pat your hands together is not a diagnostic test for cognitive decline.”So while those quick coordination challenges might be fun or stimulating, experts say, your best bet for brain health still lies in the basics: regular exercise, quality sleep, a balanced diet and staying mentally and socially active.“Factors such as poor diet, sedentary lifestyle, obesity, diabetes, hypertension, sleep problems, chronic stress and excessive alcohol can contribute to shrinkage in the brain,” Fotuhi said. “Along with genetic and environmental factors, these lifestyle and medical factors can damage small blood vessels, reduce rinsing mechanisms in the brain, cause ‘leaky brain’ and increase brain inflammation ― which over time lead to cognitive decline and Alzheimer’s disease. So rather than worrying about one task, it’s better to focus on overall brain health habits.”Ultimately, what exercise and mental stimulation mean can vary based on individuals’ abilities. “If you only have the capacity to practice hand gestures, then that’s OK too,” Winter said. But just remember that the real “hack” for keeping your brain sharp isn’t a social media exercise ― it’s a holistic approach to living a healthy, mindful and engaged life.

Under Current Guidelines, Most Lung Cancer Patients Weren't Eligible for Cancer Screening

By Ernie Mundell HealthDay ReporterMONDAY, Nov. 24, 2025 (HealthDay News) — Under current screening guidelines, almost two-thirds of Americans with...

By Ernie Mundell HealthDay ReporterMONDAY, Nov. 24, 2025 (HealthDay News) — Under current screening guidelines, almost two-thirds of Americans with lung cancer would not have qualified for the CT chest scans that could have spotted tumors early and extended their lives, new research shows. The finding hits home for 38-year-old Carla Tapia, a mother of three from Beltsville, Maryland. She smoked a bit in her youth but had kicked the habit by 18. Nevertheless, Tapia first developed respiratory symptoms in 2018, and was diagnosed with inoperable stage 4 lung cancer in 2020. After numerous chemotherapies failed, Tapia received a life-saving double-lung transplant at Northwestern Medicine in Chicago in 2024. She’s now attending college back at home in Maryland.According to Tapia, it's an ordeal timely screening might have prevented.“I keep hearing stories about young people being diagnosed with lung cancer, and if we could expand the screening guidelines, I believe more lung cancers could be caught at earlier stages, and more lives would be saved,” she said in a Northwestern Medicine news release.Current guidelines from the United States Preventive Services Task Force (USPSTF) advise annual CT chest scans for adults ages 50 to 80 who have a 20 pack-year smoking history and currently smoke or have quit within the past 15 years. According to study senior author Dr. Ankit Bharat, those eligibility guidelines are too restrictive and miss many people still at risk for the leading cancer killer.“We moved to universal age-based screening for breast and colon cancer with tremendous success, and we need to move to the same approach for lung cancer,” Bharat said in a Northwestern news release. “Chest screening offers something unique — with one low-dose scan, we can assess lungs, heart and bones comprehensively. This baseline scan becomes invaluable for monitoring their health over time,” said Bharat. He is chief of thoracic surgery and executive director of the Northwestern Medicine Canning Thoracic Institute.Lung cancer can strike anyone, including people who only smoked a short amount of time and even never-smokers. And, as happened in Tapia’s case, nearly 80% of the time lung cancers are first diagnosed in an advanced stage. The new study was published Nov. 20 in JAMA Network Open. It tracked nearly 1,000 consecutive patients whose lung cancers were treated at Northwestern Medicine.Based on their history of smoking (including never-smokers), Bharat’s group estimated that only 35% would have been eligible under USPSTF guidelines to be referred to annual lung CT scanning. Women and never-smokers made up a significant number of those who would have been excluded from eligibility for screening, the researchers said.They believe that moving to a universal screening approach — recommending lung screens for everyone ages 40 to 85 — could spot more tumors early, boost the cost-effectiveness of lung cancer care, and help level the playing field for disadvantaged Americans. According to the researchers, a typical lung CT scan takes less than 10 seconds and doesn’t require any intravenous imaging dyes. Bharat notes that the leftover effects of the COVID-19 pandemic could mean heightened risks of other lung illnesses among relatively young Americans."Nearly six years after the pandemic's start, we're seeing increasing numbers of patients with lung scarring and fibrosis from COVID-19, especially those who get reinfected with respiratory viruses," he said. “The damage compounds with each infection. Early detection through comprehensive screening can help us intervene before these conditions progress to requiring [lung] transplantation.”Northwestern’s Lung Health Center created a list of patient types who might want to consider lung screening:COVID-19 survivors who are having ongoing respiratory issues People exposed to contaminants such as wildfire smoke, industrial pollution or high radon levels People with family histories of lung disease or pulmonary fibrosis Those exposed to secondhand smoke, vaping or marijuana use Asian women and other demographics at elevated risk for lung conditions Anyone seeking baseline chest health assessment “We're seeing younger patients with respiratory problems from vaping, environmental exposures and COVID-19 who would never qualify for traditional screening,” said study co-author Dr. Scott Budinger, chief of pulmonary and critical care at the Canning Thoracic Institute.A more inclusive approach to screening “allows us to catch interstitial lung disease, pulmonary fibrosis, lung cancer and other conditions years before they'd typically be diagnosed,” he said in the news release.SOURCE: Northwestern Medicine, news release, Nov. 20., 2025Copyright © 2025 HealthDay. All rights reserved.

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