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Genetic Discrimination Is Coming for Us All

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Tuesday, November 12, 2024

The news came four years ago, at the end of a casual phone call. Bill’s family had always thought it was a freak coincidence that his father and grandfather both had ALS. But at the end of a catch-up, Bill’s brother revealed that he had a diagnosis too. The familial trend, it turned out, was linked to a genetic mutation. That meant Bill might also be at risk for the disease.An ALS specialist ordered Bill a DNA test. While he waited for results, he applied for long-term-care insurance. If he ever developed ALS, Bill told me, he wanted to ensure that the care he would need as his nerve cells died and muscles atrophied wouldn’t strain the family finances. When Bill found out he had the mutation, he shared the news with his insurance agent, who dealt him another blow: “I don’t expect you to be approved,” he remembers her saying.Bill doesn’t have ALS. He’s a healthy 60-year-old man who spends his weekends building his dream home by hand. A recent study of mutations like his suggests that his genetics increase his chances of developing ALS by about 25 percent, on average. Most ALS cases aren’t genetic at all. And yet, Bill felt like he was being treated as if he was already sick. (Bill asked to be identified by his first name only, because he hasn’t disclosed his situation to his employer and worried about facing blowback at work too.)What happened to Bill, and to dozens of other people whose experiences have been documented by disease advocates and on social media, is perfectly legal. Gaps in the United States’ genetic-nondiscrimination law mean that life, long-term-care, and disability insurers can obligate their customers to disclose genetic risk factors for disease and deny them coverage (or hike prices) based on the resulting information. It doesn’t matter whether those customers found out about their mutations from a doctor-ordered test or a 23andMe kit.  For decades, researchers have feared that people might be targeted over their DNA, but they weren’t sure how often it was happening. Now at least a handful of Americans are experiencing what they argue is a form of discrimination. And as more people get their genomes sequenced—and researchers learn to glean even more information from the results—a growing number of people may find themselves similarly targeted.When scientists were mapping the immense complexity of the human genome around the turn of the 21st century, many thought that most diseases would eventually be traced to individual genes. Consequently, researchers worried that people might, for example, get fired because of their genetics; around the same time, a federal research lab was sued by its employees for conducting genetic tests for sickle-cell disease on prospective hires without their explicit consent. In 2008, the Genetic Information Nondiscrimination Act (GINA) was signed into law, ensuring that employers couldn’t decide to hire or fire you, and health insurers couldn’t decide whether to issue a policy, based on DNA. But lawmakers carved out a host of exceptions. Insurers offering life, long-term-care, or disability insurance could take DNA into account. Too many high-risk people in an insurance pool, they argued, could raise prices for everyone. Those exceptions are why an insurer was able to deny Bill a long-term-care policy.[Read: The loopholes in the law prohibiting genetic discrimination]Cases like Bill’s are exactly what critics of the consumer-genetic-testing industry feared when millions of people began spitting into test tubes. These cases have never been tallied up or well documented. But I found plenty of examples by canvassing disease-advocacy organizations and social-media communities for ALS, breast cancer, and Huntington’s disease. Lisa Schlager, the vice president of public policy at the hereditary-cancer advocacy group FORCE, told me she is collecting accounts of discrimination in life, long-term-care, and disability insurance to assess the extent of the problem; so far, she has about 40. A man Schlager connected me with, whose genetic condition, Lynch syndrome, increases the risk for several cancers, had his life-insurance premium increased and coverage decreased; several other providers denied him a policy altogether. Kelly Kashmer, a 42-year-old South Carolina resident, told me she was denied life insurance in 2013 after learning that she had a harmful version of the BRCA2 gene. One woman I found via Reddit told me she had never tested her own DNA, but showed me documents that demonstrate she was still denied policies—because, she said, her mom had a concerning gene. (Some of the people I spoke with, like Bill, requested not to be identified in order to protect their medical privacy.)Studies have shown that people seek out additional insurance when they have increased genetic odds of becoming ill or dying. “Life insurers carefully evaluate each applicant’s health, determining premiums and coverage based on life expectancy,” Jan Graeber, a senior health actuary for the American Council of Life Insurers, said in a statement. “This process ensures fairness for both current and future policyholders while supporting the company’s long-term financial stability.” But it also means people might avoid seeking out potentially lifesaving health information. Research has consistently found that concerns about discrimination are one of the most cited reasons that people avoid taking DNA tests.For some genetically linked diseases, such as ALS and Huntington’s disease, knowing you have a harmful mutation does not enable you to prevent the potential onset of disease. Sometimes, though, knowing about a mutation can decrease odds of severe illness or death. BRCA mutations, for example, give someone as much as an 85 percent chance of developing breast cancer, but evidence shows that testing women for the mutations has helped reduce the rate of cancer deaths by encouraging screenings and prophylactic surgeries that could catch or prevent disease. Kashmer told me that her first screening after she discovered her BRCA2 mutation revealed that she already had breast cancer; had she not sought a genetic test, she may have gotten a policy, but would have been a much worse bet for the insurer. She’s now been cancer-free for 11 years, but she said she hasn’t bothered to apply for a policy again.[Read: Remember that DNA you gave 23andMe?]Even employers, which must adhere to GINA, might soon be able to hire or fire based on certain genetic risk factors. Laura Hercher, a genetic counselor and director of research at the Sarah Lawrence College Human Genetics Program, told me that some researchers are now arguing that having two copies of the APOE4 mutation, which gives people about a 60 percent chance of developing Alzheimer’s, is equivalent to a Stage Zero of the disease. If having a gene is considered equivalent to a diagnosis, do GINA’s protections still apply? The Affordable Care Act prevents health insurers from discriminating based on preexisting conditions, but not employers and other types of insurers. (The ACA may change dramatically under the coming Trump presidency anyway.) And the Americans With Disabilities Act might not apply to the gray area between what might be viewed as an early manifestation of a disease and the stage when it’s considered a disability. FORCE and other advocacy groups—including the ALS Association and the Michael J. Fox Foundation—as well as members of the National Society of Genetic Counselors, are working in a few states to pass laws that close gaps left by GINA, as Florida did in 2020, but so far they have been mostly unsuccessful.Genetic testing has only just become common enough in the U.S. that insurers might bother asking about it, Hercher said. Recently, groups like Schlager’s have been hearing more and more anecdotes. “People are so worried about genetic discrimination that they are failing to sign up for research studies or declining medically recommended care because of the concerns of what could happen to their insurance,” Anya Prince, a professor at the University of Iowa College of Law, told me. Carolyn Applegate, a genetic counselor in Maryland, told me that when patients come to her worried about a hereditary disease, she typically advises them to line up all the extra coverage they might need first—then hand over their DNA to a lab.So far, these unintended consequences of genetic testing seem to be manifesting for people with risk for rare diseases linked to single genes, which, combined, affect about 6 percent of the global population, according to one estimate. But the leading killers—heart disease, diabetes, and the like—are influenced by a yet unknown number of genes, along with lifestyle and environmental factors, such as diet, stress, and air quality. Researchers have tried to make sense of this complex interplay of genes through polygenic risk scores, which use statistical modeling to predict that someone has, say, a slightly elevated chance of developing Alzeheimer’s. Many experts think these scores have limited predictive power, but “in the future, genetic tests will be even more predictive and even more helpful and even more out there,” Prince said. Already, if you look deep enough, almost everyone’s genome registers some risk.[Read: What happens when you’re convinced you have bad genes]In aggregate, such information can be valuable to companies, Nicholas Papageorge, a professor of economics at Johns Hopkins University, told me. Insurers want to sell policies at as high a price as possible while also reducing their exposure; knowing even a little bit more about someone’s odds of one day developing a debilitating or deadly disease might help one company win out over the competition. As long as the predictions embedded in polygenic risk scores come true at least a small percentage of the time, they could help insurers make more targeted decisions about who to cover and what to charge them. As we learn more about what genes mean for everyone’s health, insurance companies could use that information to dictate coverage for ever more people.Bill still doesn’t know whether he will ever develop ALS. The average age of onset is 40 to 60, but many people don’t show symptoms until well into their 70s. Without long-term-care insurance, Bill might not be able to afford full-time nursing care if he someday needs it. People who do develop ALS become unable to walk or talk or chew as the disease progresses. “Moving people to the bathroom, changing the sheets, changing the bedpans,” Bill said—“I dread the thought of burdening my wife with all of those things.”Cases like Bill’s could soon become more common. Because scientists’ understanding of the human genome is still evolving, no one can predict all of the potential consequences of decoding it. As more information is mined from the genome, interest in its secrets is sure to grow beyond risk-averse insurers. If consumer-facing DNA-testing companies such as 23andMe change their long-standing privacy policies, go bankrupt, or are sold to unscrupulous buyers, more companies could have access to individuals’ genetic risk profiles too. (23andMe told me that it does not share customer data with insurance companies and its CEO has said she is not currently open to third-party acquisition offers.) Papageorge told me he could imagine, say, scammers targeting people at risk for Alzheimer’s, just as they often target older people who may fall for a ploy out of confusion. All of us have glitches somewhere in our genome—the question is who will take advantage of that information.

Insurers are refusing to cover Americans whose DNA reveals health risks. It’s perfectly legal.

The news came four years ago, at the end of a casual phone call. Bill’s family had always thought it was a freak coincidence that his father and grandfather both had ALS. But at the end of a catch-up, Bill’s brother revealed that he had a diagnosis too. The familial trend, it turned out, was linked to a genetic mutation. That meant Bill might also be at risk for the disease.

An ALS specialist ordered Bill a DNA test. While he waited for results, he applied for long-term-care insurance. If he ever developed ALS, Bill told me, he wanted to ensure that the care he would need as his nerve cells died and muscles atrophied wouldn’t strain the family finances. When Bill found out he had the mutation, he shared the news with his insurance agent, who dealt him another blow: “I don’t expect you to be approved,” he remembers her saying.

Bill doesn’t have ALS. He’s a healthy 60-year-old man who spends his weekends building his dream home by hand. A recent study of mutations like his suggests that his genetics increase his chances of developing ALS by about 25 percent, on average. Most ALS cases aren’t genetic at all. And yet, Bill felt like he was being treated as if he was already sick. (Bill asked to be identified by his first name only, because he hasn’t disclosed his situation to his employer and worried about facing blowback at work too.)

What happened to Bill, and to dozens of other people whose experiences have been documented by disease advocates and on social media, is perfectly legal. Gaps in the United States’ genetic-nondiscrimination law mean that life, long-term-care, and disability insurers can obligate their customers to disclose genetic risk factors for disease and deny them coverage (or hike prices) based on the resulting information. It doesn’t matter whether those customers found out about their mutations from a doctor-ordered test or a 23andMe kit.  

For decades, researchers have feared that people might be targeted over their DNA, but they weren’t sure how often it was happening. Now at least a handful of Americans are experiencing what they argue is a form of discrimination. And as more people get their genomes sequenced—and researchers learn to glean even more information from the results—a growing number of people may find themselves similarly targeted.

When scientists were mapping the immense complexity of the human genome around the turn of the 21st century, many thought that most diseases would eventually be traced to individual genes. Consequently, researchers worried that people might, for example, get fired because of their genetics; around the same time, a federal research lab was sued by its employees for conducting genetic tests for sickle-cell disease on prospective hires without their explicit consent. In 2008, the Genetic Information Nondiscrimination Act (GINA) was signed into law, ensuring that employers couldn’t decide to hire or fire you, and health insurers couldn’t decide whether to issue a policy, based on DNA. But lawmakers carved out a host of exceptions. Insurers offering life, long-term-care, or disability insurance could take DNA into account. Too many high-risk people in an insurance pool, they argued, could raise prices for everyone. Those exceptions are why an insurer was able to deny Bill a long-term-care policy.

[Read: The loopholes in the law prohibiting genetic discrimination]

Cases like Bill’s are exactly what critics of the consumer-genetic-testing industry feared when millions of people began spitting into test tubes. These cases have never been tallied up or well documented. But I found plenty of examples by canvassing disease-advocacy organizations and social-media communities for ALS, breast cancer, and Huntington’s disease. Lisa Schlager, the vice president of public policy at the hereditary-cancer advocacy group FORCE, told me she is collecting accounts of discrimination in life, long-term-care, and disability insurance to assess the extent of the problem; so far, she has about 40. A man Schlager connected me with, whose genetic condition, Lynch syndrome, increases the risk for several cancers, had his life-insurance premium increased and coverage decreased; several other providers denied him a policy altogether. Kelly Kashmer, a 42-year-old South Carolina resident, told me she was denied life insurance in 2013 after learning that she had a harmful version of the BRCA2 gene. One woman I found via Reddit told me she had never tested her own DNA, but showed me documents that demonstrate she was still denied policies—because, she said, her mom had a concerning gene. (Some of the people I spoke with, like Bill, requested not to be identified in order to protect their medical privacy.)

Studies have shown that people seek out additional insurance when they have increased genetic odds of becoming ill or dying. “Life insurers carefully evaluate each applicant’s health, determining premiums and coverage based on life expectancy,” Jan Graeber, a senior health actuary for the American Council of Life Insurers, said in a statement. “This process ensures fairness for both current and future policyholders while supporting the company’s long-term financial stability.” But it also means people might avoid seeking out potentially lifesaving health information. Research has consistently found that concerns about discrimination are one of the most cited reasons that people avoid taking DNA tests.

For some genetically linked diseases, such as ALS and Huntington’s disease, knowing you have a harmful mutation does not enable you to prevent the potential onset of disease. Sometimes, though, knowing about a mutation can decrease odds of severe illness or death. BRCA mutations, for example, give someone as much as an 85 percent chance of developing breast cancer, but evidence shows that testing women for the mutations has helped reduce the rate of cancer deaths by encouraging screenings and prophylactic surgeries that could catch or prevent disease. Kashmer told me that her first screening after she discovered her BRCA2 mutation revealed that she already had breast cancer; had she not sought a genetic test, she may have gotten a policy, but would have been a much worse bet for the insurer. She’s now been cancer-free for 11 years, but she said she hasn’t bothered to apply for a policy again.

[Read: Remember that DNA you gave 23andMe?]

Even employers, which must adhere to GINA, might soon be able to hire or fire based on certain genetic risk factors. Laura Hercher, a genetic counselor and director of research at the Sarah Lawrence College Human Genetics Program, told me that some researchers are now arguing that having two copies of the APOE4 mutation, which gives people about a 60 percent chance of developing Alzheimer’s, is equivalent to a Stage Zero of the disease. If having a gene is considered equivalent to a diagnosis, do GINA’s protections still apply? The Affordable Care Act prevents health insurers from discriminating based on preexisting conditions, but not employers and other types of insurers. (The ACA may change dramatically under the coming Trump presidency anyway.) And the Americans With Disabilities Act might not apply to the gray area between what might be viewed as an early manifestation of a disease and the stage when it’s considered a disability. FORCE and other advocacy groups—including the ALS Association and the Michael J. Fox Foundation—as well as members of the National Society of Genetic Counselors, are working in a few states to pass laws that close gaps left by GINA, as Florida did in 2020, but so far they have been mostly unsuccessful.

Genetic testing has only just become common enough in the U.S. that insurers might bother asking about it, Hercher said. Recently, groups like Schlager’s have been hearing more and more anecdotes. “People are so worried about genetic discrimination that they are failing to sign up for research studies or declining medically recommended care because of the concerns of what could happen to their insurance,” Anya Prince, a professor at the University of Iowa College of Law, told me. Carolyn Applegate, a genetic counselor in Maryland, told me that when patients come to her worried about a hereditary disease, she typically advises them to line up all the extra coverage they might need first—then hand over their DNA to a lab.

So far, these unintended consequences of genetic testing seem to be manifesting for people with risk for rare diseases linked to single genes, which, combined, affect about 6 percent of the global population, according to one estimate. But the leading killers—heart disease, diabetes, and the like—are influenced by a yet unknown number of genes, along with lifestyle and environmental factors, such as diet, stress, and air quality. Researchers have tried to make sense of this complex interplay of genes through polygenic risk scores, which use statistical modeling to predict that someone has, say, a slightly elevated chance of developing Alzeheimer’s. Many experts think these scores have limited predictive power, but “in the future, genetic tests will be even more predictive and even more helpful and even more out there,” Prince said. Already, if you look deep enough, almost everyone’s genome registers some risk.

[Read: What happens when you’re convinced you have bad genes]

In aggregate, such information can be valuable to companies, Nicholas Papageorge, a professor of economics at Johns Hopkins University, told me. Insurers want to sell policies at as high a price as possible while also reducing their exposure; knowing even a little bit more about someone’s odds of one day developing a debilitating or deadly disease might help one company win out over the competition. As long as the predictions embedded in polygenic risk scores come true at least a small percentage of the time, they could help insurers make more targeted decisions about who to cover and what to charge them. As we learn more about what genes mean for everyone’s health, insurance companies could use that information to dictate coverage for ever more people.

Bill still doesn’t know whether he will ever develop ALS. The average age of onset is 40 to 60, but many people don’t show symptoms until well into their 70s. Without long-term-care insurance, Bill might not be able to afford full-time nursing care if he someday needs it. People who do develop ALS become unable to walk or talk or chew as the disease progresses. “Moving people to the bathroom, changing the sheets, changing the bedpans,” Bill said—“I dread the thought of burdening my wife with all of those things.”

Cases like Bill’s could soon become more common. Because scientists’ understanding of the human genome is still evolving, no one can predict all of the potential consequences of decoding it. As more information is mined from the genome, interest in its secrets is sure to grow beyond risk-averse insurers. If consumer-facing DNA-testing companies such as 23andMe change their long-standing privacy policies, go bankrupt, or are sold to unscrupulous buyers, more companies could have access to individuals’ genetic risk profiles too. (23andMe told me that it does not share customer data with insurance companies and its CEO has said she is not currently open to third-party acquisition offers.) Papageorge told me he could imagine, say, scammers targeting people at risk for Alzheimer’s, just as they often target older people who may fall for a ploy out of confusion. All of us have glitches somewhere in our genome—the question is who will take advantage of that information.

Read the full story here.
Photos courtesy of

First, the frogs died. Then people got sick.

An emerging area of research is uncovering hidden links between nature and human health.

First, the frogs died. Then people got sick.An emerging area of research is uncovering hidden links between nature and human health.This reporting was supported by the Pulitzer Center....moreThis reporting was supported by the Pulitzer Center....moreNovember 14, 2025 at 6:00 a.m. EST9 minutes agoALTOS DE CAMPANA NATIONAL PARK, Panama — Brian Gratwicke’s lunch box was full of frogs.Kneeling on the muddy rainforest floor, the biologist opened his red Coleman cooler and scooped one up. It was a Pratt’s rocket frog — about the size of a walnut, sporting black-and-white racing stripes. Gratwicke deposited the frog in a small mesh tent, a “catio” for indoor pets to glimpse the outdoors, and encouraged it to acclimate to its transitional home.“There you go,” he told it. “Look at all that nice leaf litter.” The frog darted into the carpet of leaves, unaware it had just leaped into a high-stakes experiment.Conservation biologist Brian Gratwicke searches with his team for frogs in Altos de Campana National Park in Panama.Nate Weisenbeck, a research intern with the Panama Amphibian Rescue and Conservation Project, checks on how a pair of Pratt’s rocket frogs are acclimating to the forest.Gratwicke is a conservation biologist who leads amphibian work at the Smithsonian’s National Zoo and Conservation Biology Institute. He had flown to Panama, in the middle of rainy season, to help resurrect frog species that had vanished from the cloud forest decades ago.Whether these amphibians can strike out on their own and thrive here again is uncertain.What is becoming increasingly clear is that without them, humans are in trouble. It turns out that frogs — in biblical times regarded as a plague — are actually guardians against disease.50 Species that Save UsThis series highlights emerging research on how plants and animals protect human health – and how their disappearance is already sickening thousands of people around the world. Explore these connections in our illustrated, interactive species cards.As dozens of frog species have declined across Central America, scientists have witnessed a remarkable chain of events: With fewer tadpoles to eat mosquito larvae, rates of mosquito-borne malaria in the region have climbed, resulting in a fivefold increase in cases.The discovery of this link is part of an emerging area of research in which ecologists and economists are trying to calculate the costs of species decline.They are revealing hidden ways that thriving populations of many plants and animals — including wolves, bats, birds and trees — underpin humanity’s well-being.They are learning that without saving nature, we cannot save ourselves.The mystery of the vanishing frogsAt first, no one knew why frogs seemed to be disappearing everywhere.In Texas, some herpetologists thought egrets were eating them. In Connecticut, people accused raccoons. In Brazil, they blamed a bout of chilly weather. But the fact that so many frogs were vanishing from so many places in the early 1990s suggested something widespread but invisible was behind the decline.Karen Lips was a graduate student at the time, working with amphibians in Costa Rica, near the border with Panama. During a trip there in 1993, she couldn’t find the toads she had been studying. “Almost everything was gone,” she recalled. At first, she blamed the weather, her headlamp, her searching technique.Then she remembered a related toad species had disappeared a few hundred miles to the north. It dawned on her: Perhaps a frog-killing “wave” was sweeping from mountain to mountain.Weisenbeck works with harlequin frogs raised at the Panama Amphibian Rescue and Conservation Project in Gamboa.Lemur leaf frogs are grouped in a breeding tank with multiple males and females at the Panama Amphibian Rescue and Conservation Project.Whatever it was, she wanted to get ahead of it. She set up camp farther east, in a cloud forest in Panama. She thought she’d have many years to study the 40-odd species of frogs there. But by 1996, many of the ones she was picking up were leathery and lethargic.“Sometimes they would make one jump and it would be their last bout of energy,” recalled Lips, today an ecologist at the International Institute for Applied Systems Analysis. “They’d make a big jump to try and escape. And then they couldn’t move anymore at all, and they would just die there.”After she helped publish a photo of an infection on the frogs’ skin, herpetologists studying wild frogs in Australia and captive ones at the National Zoo realized they were all dealing with the same disease: a fungus that would be dubbed Batrachochytrium dendrobatidis, or Bd for short.The researchers swab a yellow-flecked glass frog to assess the prevalence of Bd in wild frog communities in Altos de Campana National Park.Thought to have originated in Asia or Africa, Bd may have hitched a ride on ships or planes to traverse otherwise insurmountable oceans. It now coats every continent except Antarctica (where there are no frogs).The microscopic pathogen kills by burrowing into an amphibian’s sensitive skin, blocking electrolytes and sapping muscles of their strength. Ultimately, an infected frog becomes so fatigued that its heart stops.As the fungus swept eastward through Panama, Gratwicke and his colleagues raced to rescue as many frogs as they could. They persuaded a shipping company to donate seven containers to a Smithsonian facility an hour outside Panama City. There, along the Panama Canal, they built a makeshift ark, stacking each container floor-to-ceiling with terrariums full of frogs for a captive breeding program.The Smithsonian focused on saving nine species it assessed to be in the direst state. “It’s absolute triage,” Gratwicke said. “We can’t look after 200 species.”Among those targeted for preservation was the Panamanian golden frog, a national icon and symbol of good luck that is depicted on banners and beer cans.“It’s a huge weight of responsibility on our shoulders,” Gratwicke said. “Because if we screw this up, we screw it up for an entire species.”This year, the researchers also brought into captivity a population of Pratt’s rocket frogs that had disappeared in the national park but survived elsewhere, possibly because they had developed some immunity to the fungus. Gratwicke and his colleagues were relocating two dozen of those potentially resistant frogs to Altos de Campana. After two weeks, the researchers would unzip them from the tents, with the hope that the transplanted frogs might help repopulate the park.Globally, frog populations have crashed as a result of Bd. The fungus has affected more than 500 amphibian species, decimating at least 90 to the point where they are thought to be extinct in the wild. For the researchers watching it all unfold over the past three decades, it was clear a frog apocalypse was underway. The fungus, along with climate change and habitat loss, has made amphibians the most vulnerable group of vertebrates on Earth.Lips began studying the cascading effects of these massive losses. She found algae thrived in spots where there were no tadpoles to eat it. Snake populations, meanwhile, dwindled with fewer adult frogs to eat.When describing this upheaval in a call with other scientists, she piqued the interest of Michael Springborn, an environmental economist at the University of California at Davis. “I’d heard a little bit about Bd,” he recalled, “but I was embarrassed to learn that I didn’t really understand how impactful that had been.” The two decided to work together.Lemur leaf frogs are among the lab-raised specimens at the Panama Amphibian Rescue and Conservation Project.With statistical tools more commonly used in economics, they mapped the frog die-offs and spread of the fungus county-by-county across Costa Rica and Panama.Then they compared that spread to county-level health records of malaria in humans. They found a striking pattern: a fivefold spike in malaria cases after the fungus arrived and the frogs died. Lips, Springborn and their colleagues published the discovery in 2022 in the journal Environmental Research Letters.The region’s tapered shape, bound on either side by the Caribbean and the Pacific, allowed them to track the spread of the disease in detail. “We got lucky in a sense that there’s this … narrow strip where you had Bd arguably channeled through,” Springborn said.Some herpetologists, Lips said, would be content to stay in their lane and just “count the frogs.” But she anticipated that “if we could link it to people, maybe we could get more traction. Maybe people would care.”Biologists have long documented ways in which people benefit from nature — what, in academic circles, are called “ecosystem services.” Bees pollinate crops, trees suck heat-trapping carbon dioxide out of the air, and coral reefs guard coastal communities from storms and foster fish for food.But the interdisciplinary effort to uncover the relationship between biodiversity and human health — an approach dubbed “One Health” — is just beginning to tease out even deeper connections.The researchers are working toward the release of Panamanian golden frogs, an icon of the country.In the United States, researchers have shown that a collapse of insect-eating bat populations prompted farmers to use more pesticide on crops, which in turn led to a higher human infant mortality rate.Around the Great Lakes, the reemergence of gray wolves has had the surprising effect of keeping motorists safe. The canines prowl along roads while hunting, spooking deer from crossing and reducing collisions with cars.Also in North America, invasive emerald ash borers devastated ash trees, contributing to elevated temperatures and an increase in cardiovascular and respiratory deaths.India may have witnessed the most astounding ecological breakdown of them all. After vultures experienced a mass die-off, the livestock carcasses they once scavenged piled up. Packs of feral dogs took the place of vultures, resulting in a rise in deaths from rabies.Eyal Frank, a University of Chicago economist who helped connect the dots in the bat and vulture case studies, said we often don’t realize how crucial a plant or animal is to our well-being until it is gone.“Why preserve biodiversity?” Frank said. “We might not realize now that this species is important. But we might realize in the future that it’s important.”By 2012, the frog-killing fungus had conquered Panama, reaching its easternmost point, the Darién Gap.A remote and roadless jungle, the area is known as a treacherous stretch for migrants trying to make their way from North to South America. The resident population is small and mostly made up of Indigenous tribes.Jando Mejia, from the seminomadic Wounaan people, figures he was bitten when he was visiting his mother there in 2023. When a mosquito latched onto his skin and sucked his blood, it must have dropped a single-celled parasite called a plasmodium into his body.Within days the parasite began wreaking havoc, invading and multiplying within his red blood cells. His eyes and tongue turned yellow. His head felt like it was splitting open with pain.“I couldn’t taste food,” he said. “I lost my appetite, and I felt dizzy and weak. I couldn’t do anything.”Mejia, 23, believes he contracted malaria in eastern Panama.Mejia was at that point staying with his sister in central Panama. Her house is on concrete stilts to deter snakes and other wildlife, but its plywood walls and open-air windows provide little protection from buzzing mosquitos. Smoke wafts from spiral-shaped repellents to keep the insects away. Nearby, vendors in the village sell golden frog figurines.His sister set up a bed for him on the floor. His mother made the journey from the Darién Gap to help. “I was in bed for a week,” he said. “I could hardly remember anything.”Even after the worst of the symptoms subsided, it was weeks before he had enough strength to return to his $15-a-day job on a farm growing coffee and plantains.“He wasn’t normal,” his sister, Chanita Mejia, recalled. “Even climbing a small hill was hard. He felt tired.”By the time he could go back to work, he had lost out on a month of income.Telbinia Toscon, a traditional craftswoman in the Embera village, lost her mother to malaria.Frogs are a recurring image in Panamanian crafts.No single case of malaria can be attributed to the wave of frog deaths. And other factors, too, may have contributed to the rise in cases. José Ricardo Rovira, a mosquito researcher at Indicasat, a Panamanian institute, noted that paths made by migrants crisscrossing the Darién have further enabled the spread of malaria-carrying mosquitos.But Springborn, Lips and their colleagues estimate there were tens of thousands of additional cases of the disease in Panama and Costa Rica in the decade following the amphibian decline. Although it’s difficult to estimate, that increase in cases would have led to “a handful” of additional deaths each year, Springborn said.Rovira knows how debilitating the disease can be. He vividly remembers the fever and chills he experienced after twice contracting malaria while setting mosquito traps in the Darién.He said he doesn’t fear malaria, but has learned to respect it. Now 75, he appreciates he must be cautious. “I’m not going out to the field much anymore,” he said.Working to restore the frogsOn Gratwicke’s recent Panama trip, after depositing the Pratt’s rocket frogs in their tent, he turned to the question of how much Bd was still out there.He bounded down a series of waterfalls on a rumbling creek, sweeping his flashlight along the muddy embankment. The light caught a glint of yellow. It was a Panama rocket frog, a related species. True to its name, it shot off after being spotted. The hunt was on.With a stick, Gratwicke prodded the fugitive frog into the water. “Just wait, he’ll come up,” he said leaning over the stream. The birdlike chirps of rocket frogs used to fill this gully, he explained. Now, save for the rush of the water, it was mostly silent.“Oh, I got it!” Gratwicke yelped after reaching his gloved hands into the stream. Pulling out a long cotton swab, he dabbed the frogs’ feet, thighs and belly before letting it go. (Lab tests on the swabs would later reveal that Bd was on a third of the frogs plucked from the water that day.)Gratwicke and his team listen to frog calls while walking through Altos de Campana National Park.Conservation scientists Julie Dogger, Oliver Granucci and Orlando Garces check on tadpole development in Altos de Campana National Park. Next stop was the encampment of a crowned tree frog. This chocolate brown frog had been bred in a Smithsonian lab, and after two weeks acclimating to the forest, it was ready for release — into a still perilous place.Nate Weisenbeck, Gratwicke’s colleague from the Smithsonian, reached up and unlatched the front of a mesh cube nailed to a tree teetering on the mountainside.“This is a pilot,” Gratwicke said. “Because it’s the first time this has ever been done, you can’t really predict all the ways in which things can go wrong.”The researchers are trying to set their frogs up with the best shot at survival, but don’t know if they will succumb to the fungus or other predators. (The work is supported financially by the Bezos Earth Fund, a philanthropic initiative of Washington Post owner Jeff Bezos, as well as the Cheyenne Mountain Zoo, Zoo New England and the Panamanian government.)Weisenbeck had installed a variety of possible shelters for the frog to choose next: a hollow stalk of bamboo, a stack of black plastic pots, a wooden birdhouse.When the researchers came back about six hours later, wearing headlamps to navigate the pitch-black jungle at night, all those potential homes were empty.Weisenbeck unfurled a six-pronged antenna on a device that beeped to indicate whether he was homing in on the tracker tied to the frog’s back.A metamorphosing lemur leaf frog tadpole hangs on the edge of Dogger’s net. A crowned tree frog wears a radio transmitter to enable tracking within the national park.He circled the tree: beep… beep…He was careful with his feet, so as not to inadvertently step on a frog. The device grew louder. Beep… Beep…He twisted to prevent the antenna from getting tangled in the vegetation. BEEP… BEEP… BEEP…“Well done, Nate,” Gratwicke said. Weisenbeck bent down to capture one last photo of his frog, resting on a cigar plant about 30 feet from the tree.“Yeah, this could be the last time we see him,” Weisenbeck said. “He’s wild.”Two variable harlequin frogs at the Panama Amphibian Rescue and Conservation Project in Gamboa.About this storyThis article is part of The Washington Post’s “Species That Save Us” series, highlighting hidden links between nature and human health. Photos and video by Melina Mara. Design and development by Hailey Haymond. Editing by Marisa Bellack, Juliet Eilperin, John Farrell, Dominique Hildebrand and Joe Moore. Copy editing by Mike Cirelli.

Not so Golden Brown: DJ plays 24-hours of No 2s in Lake District sewage protest

Radio host uses chart songs that didn’t quite make top spot to highlight issue of Windermere pollutionIf you Sit Down and wonder why Britain’s streams, rivers and lakes are so filthy, you’re probably Holding Out for a Hero to halt this Scandalous discharge of sewage.Step forward the Lake District Radio DJ Lee Durrant, who will go Radio Ga Ga with a 24-hour live broadcasting marathon on Friday, playing songs that peaked at No 2 in the charts to highlight the ongoing stench of not quite Golden Brown “number twos” floating downstream. Continue reading...

If you Sit Down and wonder why Britain’s streams, rivers and lakes are so filthy, you’re probably Holding Out for a Hero to halt this Scandalous discharge of sewage.Step forward the Lake District Radio DJ Lee Durrant, who will go Radio Ga Ga with a 24-hour live broadcasting marathon on Friday, playing songs that peaked at No 2 in the charts to highlight the ongoing stench of not quite Golden Brown “number twos” floating downstream.If you’re fuming about the injustice of Cry Me a River or Born Slippy being left off the top spot, you may take comfort from pop classics being coopted to fight the injustice of illegal sewage spills, which is risking human health and killing wildlife in the Lake District, despite its status as a national park and world heritage site.“What’s more shocking? Fairytale of New York never making it to Christmas No 1, or United Utilities dumping sewage into Windermere and paying themselves huge dividends?” said Durrant, who begins his broadcasting marathon at 8am on 14 November. “We’re based in the Lake District so we’re passionate about what’s happening to our lakes, but it’s become a wider issue across the country and around the world with sewage-dumping in what we’d assume would be clean waterways.”skip past newsletter promotionThe planet's most important stories. Get all the week's environment news - the good, the bad and the essentialPrivacy Notice: Newsletters may contain information about charities, online ads, and content funded by outside parties. If you do not have an account, we will create a guest account for you on theguardian.com to send you this newsletter. You can complete full registration at any time. For more information about how we use your data see our Privacy Policy. We use Google reCaptcha to protect our website and the Google Privacy Policy and Terms of Service apply.after newsletter promotionBetween playing number twos with riverine resonances from Take That’s The Flood to Dirty Cash by the Adventures of Stevie V, Durrant will be joined on the community radio station by guests including campaigners from Save Windermere to Surfers Against Sewage, environmental experts and representatives from water companies.Windermere was found to have high levels of bacteria found in human faeces throughout this summer, according to comprehensive analysis of water quality in England’s largest lake. Only 14% of England’s rivers and lakes meet good ecological standards.“I’m sort of looking forward to it and sort of dreading it,” said Durrant of his No 2 marathon. “I’m predicting the witching hour of 3am will be when I’ll struggle. I might need to play some heavy rock to get me through that.”Winds of Change might go down well in the Lakes.

Fossil fuel projects around the world threaten the health of 2bn people – report

Exclusive: ‘Deep-rooted injustices’ affect billions of people due to location of wells, pipelines and other infrastructureA quarter of the world’s population lives within three miles (5km) of operational fossil fuel projects, potentially threatening the health of more than 2 billion people as well as critical ecosystems, according to first-of-its-kind research.A damning new report by Amnesty International, shared exclusively with the Guardian, found that more than 18,300 oil, gas and coal sites are currently distributed across 170 countries worldwide, occupying a vast area of the Earth’s surface. Continue reading...

A quarter of the world’s population lives within three miles (5km) of operational fossil fuel projects, potentially threatening the health of more than 2 billion people as well as critical ecosystems, according to first-of-its-kind research.A damning new report by Amnesty International, shared exclusively with the Guardian, found that more than 18,300 oil, gas and coal sites are currently distributed across 170 countries worldwide, occupying a vast area of the Earth’s surface.Proximity to drilling wells, processing plants, pipelines and other fossil fuel facilities elevates the risk of cancer, respiratory conditions, heart disease, premature birth and death, as well as posing grave threats to water supplies and air quality, and degrades land.Almost half a billion (463 million) people, including 124 million children, now live within 0.6 miles (1km) of fossil fuels sites, while another 3,500 or so new sites are currently proposed or under development that could force 135 million more people to endure fumes, flares and spills, according to Extraction Extinction: Why the Lifecycle of Fossil Fuels Threatens Life, Nature, and Human Rights.Most active projects have created pollution hotspots, turning nearby communities and critical ecosystems into so-called sacrifice zones – heavily contaminated areas where low-income and marginalized groups bear the disproportionate burden of exposure to pollution and toxins.The report details the devastating health toll from extraction, processing and transportation, as well as demonstrating how leaks, flares and construction destroy irreplaceable natural ecosystems and undermine human rights – particularly of those living near oil, gas and coal infrastructure.It comes as world leaders, excluding the US – the largest historical emitter of greenhouse gases – gather in Belém, Brazil, for the 30th annual climate negotiations amid growing frustration at the lack of progress in phasing out fossil fuels, which are driving planetary collapse and human rights violations.“The fossil fuel industry and its state sponsors have argued for decades that human development requires fossil fuels. But we know that under the guise of economic growth, they have instead served greed and profits without red lines, violated rights with near-complete impunity, and destroyed the atmosphere, biosphere and oceans,” said Agnès Callamard, secretary general of Amnesty International.“Cop30 leaders must keep people, and not profits and power, at the heart of negotiations by committing to a full, fast, fair and funded fossil-fuel phase-out and just transition to sustainable energy for all.”Cop30 takes place as the Philippines, Mexico and Jamaica are reeling from superstorms that were intensified by warmer atmospheric and ocean temperatures, with states under growing pressure to take decisive action to regulate fossil fuel companies and end extraction, subsidies, licenses and consumption in order to comply with the landmark ruling by the international court of justice.Last week, the Guardian revealed how more than 5,350 fossil fuel industry lobbyists have been given access to the UN climate talks in the past four years, blocking climate action while their paymasters drill for record quantities of oil and gas.The quantitative analysis is based on a first-of-its-kind mapping exercise by researchers at Better Planet Laboratory (BPL) at the University of Colorado Boulder, who compared data on the known locations of fossil fuel infrastructure sites with census data, and datasets on critical ecosystems, greenhouse gas emissions and Indigenous peoples’ land.A third of all operational oil, coal and gas sites overlap with one or more critical ecosystems such as a wetland, forest or river system that is rich in biodiversity and critical for carbon sequestration or where environmental degradation or disaster could lead to ecosystem collapse, researchers found.The true global scale is probably higher due to gaps in the documentation of fossil fuel projects and limited census data across countries.The report also includes testimonies from Indigenous land defenders in Canada and coastal communities in Senegal, as well as fishers in Colombia and Brazil and Amazonian leaders in Ecuador fighting against gas flaring, that were conducted in partnership with Columbia Law School’s Smith Family Human Rights Clinic.skip past newsletter promotionThe planet's most important stories. Get all the week's environment news - the good, the bad and the essentialPrivacy Notice: Newsletters may contain information about charities, online ads, and content funded by outside parties. If you do not have an account, we will create a guest account for you on theguardian.com to send you this newsletter. You can complete full registration at any time. For more information about how we use your data see our Privacy Policy. We use Google reCaptcha to protect our website and the Google Privacy Policy and Terms of Service apply.after newsletter promotionThe findings reveal deep-seated environmental injustice and racism in exposure to oil, gas and coal industries.Indigenous peoples, who account for 5% of the world’s population, are disproportionately exposed to life-shortening fossil fuel infrastructure, with one in six sites located on Indigenous territories.“We’re experiencing intergenerational battle fatigue … We physically won’t survive [this]. We were never the instigators but we have taken the brunt of all the violence,” said Wet’suwet’en land defender Tsakë ze’ Sleydo’ (Molly Wickham), describing the imminent construction of new compressors for a fossil gas pipeline on Indigenous lands in British Columbia, Canada.“When we rise up to defend the Yin’tah [Wet’suwet’en territory], we are criminalized.”The expansion of fossil fuels has also been linked with land grabs, cultural pillage, community division and loss of livelihoods, as well as violence, online threats and lawsuits, both criminal and civil, against community leaders peacefully opposing the construction of pipelines, drilling projects and other infrastructure.“We are not after money; we only want what is ours. We just want to fish in Guanabara Bay, it’s our right. And they are taking our rights,” said Bruno Alves de Vega, an urban artisanal fisher from Rio de Janeiro, Brazil.Fossil fuels affect every part of the human body, posing especially severe risks for children, older people and pregnant people that risk harm to the health of future generations, according to the UN special rapporteur on climate change who has called for criminal penalties against those peddling disinformation about the climate crisis and a total ban on fossil fuel industry lobbying and advertising.“The climate crisis is a manifestation and catalyst of deep-rooted injustices,” added Callamard from Amnesty. “The age of fossil fuels must end now.”

Air quality alert for Deschutes County Wednesday

An air quality alert was reported by the National Weather Service on Monday at 5:15 p.m. in effect until Wednesday at 3 p.m. for Deschutes County.

An air quality alert was reported by the National Weather Service on Monday at 5:15 p.m. in effect until Wednesday at 3 p.m. for Deschutes County."Oregon Department of Environmental Quality has issued an Air Quality Advisory. until 3 p.m. Wednesday. A Smoke Air Quality Advisory has been issued. Wildfires burning in the region combined with forecasted conditions will cause air quality to reach unhealthy levels. Pollutants in smoke can cause burning eyes, runny nose, aggravate heart and lung diseases, and aggravate other serious health problems. Limit outdoor activities and keep children indoors if it is smoky. Please follow medical advice if you have a heart or lung condition," comments the weather service.Guidance for air quality alerts: Insights from the weather serviceWhen an air quality alert pops up on the radar, deciphering its implications is crucial. These alerts, issued by the weather service, come with straightforward yet essential guidance to ensure your safety:Prioritize indoor stay:If it's within your means, stay indoors, especially if you have respiratory issues, health concerns, or fall within the senior or child demographics.Trim outdoor activities:When venturing outside is unavoidable, restrict your time outdoors solely to essential activities. Reducing exposure is paramount.Reduce pollution contributors:Be conscious of activities that contribute to pollution, such as driving cars, using gas-powered lawnmowers, or relying on motorized vehicles. Curtail their use during air quality alerts.A no to open burning:Refrain from igniting fires with debris or any other materials during air quality alerts. Such practices only contribute to the problem of poor air quality.Stay well-informed:Stay updated of developments by tuning in to NOAA Weather Radio or your preferred weather news source. Being well-informed empowers you to make informed decisions regarding outdoor pursuits during air quality alerts.Focus on respiratory health:If you have respiratory problems or underlying health conditions, exercise extra caution. These conditions can increase your vulnerability to adverse effects from poor air quality.By adhering to the advice from the weather service, you can enhance your safety during air quality alerts while reducing your exposure to potentially harmful pollutants. Stay aware, stay protected, and make your health a top priority.If you purchase a product or register for an account through a link on our site, we may receive compensation. By using this site, you consent to our User Agreement and agree that your clicks, interactions, and personal information may be collected, recorded, and/or stored by us and social media and other third-party partners in accordance with our Privacy Policy.

Multiple Sclerosis Explained: Symptoms, Risk Factors & How It’s Treated

By Dr. Aaron Bower, Assistant Professor of Neurology at Yale School of Medicine HealthDay ReporterMONDAY, Nov. 10, 2025 (HealthDay News) — Multiple...

MONDAY, Nov. 10, 2025 (HealthDay News) — Multiple sclerosis (MS) is one of the most common autoimmune diseases affecting the brain and spinal cord, with 2.9 million people estimated to be living with the disease worldwide.As MS is an autoimmune disease, damage is caused by inappropriate actions of the body’s infection-fighting (immune) cells. The damage typically involves myelin, the outer covering of the cells that reside in the brain and spinal cord. This impedes the electrical signals necessary for the brain and spine to function properly.The damage can lead to both sudden “flares” of inflammation and a slow worsening of symptoms over time. Historically, MS has been broken down into specific subtypes, as detailed below. But the reality of the disease may be better understood as a spectrum that likely started even before symptoms were noticed.Relapsing and remitting MS is:The most common subtype (85% of cases)  Characterized by flares of inflammation, known as “relapses” Separated by periods, known as “remissions,” when patients feel relatively normal  Primary progressive MS is: The less common subtype (10% to 15% of cases)  Characterized by consistent worsening of symptoms over months to years  Not characterized with clear “flares” or periods of stability  Secondary progressive MS: Initially follows a course like that of relapsing and remitting MS  Evolves over time, with patients noting a consistent worsening of symptoms in the absence of any clear “flares” What are the symptoms of multiple sclerosis? Since MS can affect any part of the brain or spinal cord, patients can present with a wide variety of symptoms, depending on where the damage has taken place.In patients with the most common subtype, relapsing and remitting, these symptoms will typically come on over days and improve over weeks to months.Common initial symptoms include: Painful loss or blurred vision Double vision  Face drooping on one side   Slurring words  Room-spinning dizziness and unsteadiness  Weakness in arms and/or legs  Numbness and tingling in arms and/or legs Difficulty with fine motor tasks (such as typing, buttoning a shirt and eating) Difficulty walking, possibly leading to falls  Electric shock-like sensation down the spine when touching chin to chest (“Lhermitte’s sign”)  Tight, squeezing sensation around the chest or belly (“MS hug”) What are the causes and risk factors of multiple sclerosis? There is no single cause of multiple sclerosis. It likely results from interactions between genetic and environmental risk factors. How is multiple sclerosis diagnosed? A diagnosis of MS generally requires a doctor to pursue several different tests during the initial evaluation. These tests help rule out other possible causes and provide evidence that supports a diagnosis of MS. Blood work To look for evidence of other diseases (including infection, inflammation, vitamin deficiencies, for example) Imaging: MRI of the brain and spine  Procedure: Lumbar puncture  A neurologist may also recommend evaluations by additional medical providers. This can include an ophthalmologist (eye doctor) who can look for evidence of MS affecting the optic nerve that connects the eye to the brain.This can be achieved through non-invasive testing, such as optical coherence tomography (OCT), which examines the thickness of the nerves at the back of the eye, or visual evoked potentials (VEPs), which assess the function of the optic nerve.How is multiple sclerosis treated? MS treatment is provided on two fronts: 1) Treatment of active inflammation. 2) Prevention of new inflammation and damage to the brain and spine. If a patient is having active inflammation due to MS (“flare”), a provider will typically recommend treatment with steroids. Steroids quickly reduce inflammation in the body to speed recovery. This is generally administered by IV infusion over three to five days.To avoid recurrent “flares” and the side effects of frequent steroid use, however, the key to MS treatment is prevention.Preventive medications in MS are referred to as disease-modifying therapies (DMTs). These medications should be started as early as possible to limit damage to the brain and spine. The U.S. Food and Drug Administration (FDA) has approved many DMTs for relapsing-remitting MS. Each medication can vary in effectiveness, side effects and how it is administered (pills, injections or infusions). Ultimately, the choice of treatment is an individualized discussion between the patient and provider. There are fewer options for secondary and primary progressive MS. A single medication (Ocrevus) is currently FDA-approved to treat this subtype of MS.What is it like living with multiple sclerosis? Living with MS has changed dramatically as more effective treatments have been developed, with patients generally acquiring less disability and limitations over time.However, many people with MS can continue to struggle with “day-to-day” symptoms that require additional treatment. Possible “day-to-day” symptoms include: . Fatigue  Slowed processing speed and memory impairments  Issues with mood (depression, anxiety)  Problems with urination and bowel movements  Tingling and burning sensations  Muscle tightness and cramping  Walking difficulties and instability  Heat intolerance  Given the variety of symptoms one can face with MS, a patient’s neurologist will work with other medical providers to optimize care.Additional team members could include physical therapists, occupational therapists, speech therapists, physiatrists, mental health care providers, and specialists in the areas of eye, bladder, GI and sleep.Together, the health care team will work with the patient to prevent and treat the complications of MS, allowing patients to live life as they want.Dr. Aaron Bower is an Assistant Professor of Neurology at the Yale School of Medicine. He is a board-certified neurologist and completed fellowship training in Multiple Sclerosis and Neuroimmunology. He specializes in treating patients with inflammatory disorders of the central nervous system such as Multiple sclerosis, Neuromyelitis Optica, Autoimmune encephalitis, MOG-associated disease, and the neurologic sequelae of systemic Rheumatologic disease.Copyright © 2025 HealthDay. All rights reserved.

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